Obesity Management

Tirzepatide (Mounjaro, Zepbound), a glucagon-like peptide-1 (GLP-1) medication, demonstrates improved diabetes control and decreases in insulin requirements.

ASC30, an investigational glucagon-like 1-peptide receptor agonist, demonstrates mean weight reductions from baseline of 4.3% and 6.3% for 2 separate cohorts.

The Institute for Clinical and Economic Review assessed the formularies of 11 payers, covering 57 million people, to determine access to drugs that the organization had reviewed for cost effectiveness in 2022.

For weight loss and antihypertensive effects on systolic and diastolic blood pressure, semaglutide also had increased effects.

Recently, there has been concern around glucagon-like peptide-1 receptor agonists and increase the risk of thyroid cancer, with liraglutide having a black box warning label for the disease.

Researchers addressed the factors leading to and the rates of discontinuation and reinitiation of GLP-1 RAs among adults with obesity.

In a phase 1b/2a clinical trial, investigators evaluated the once weekly subcutaneous drug for safety, tolerability, pharmacokinetics, and proof-of-concept.

Taking once-weekly subcutaneous semaglutide does not increase depression symptoms or suicidal ideation in patients with obesity.

In a post hoc secondary analysis of the BP-CATCH trial, researchers explored the best ways of screening children with high blood pressure and managing their care.

Adolescent obesity rates have risen in recent years, and a number of treatment options can be taken to help reduce the risk of a variety of associated medical problems.

To highlight the effectiveness of pediatric obesity treatment, researchers measured its impact on morbidity and mortality in young adulthood.

For adults with obesity but no diabetes diagnosis, researchers searched for the key factors leading to semaglutide initiation.

Researchers wanted to better understand the accuracy of advertising practices behind websites selling compounded GLP-1 RAs.

Sarah Gray, PharmD, GAICD, explored the unique combination of being both a pharmacist and nutritionist.

RGT-075 from Regor Therapeutics demonstrated a statistically significant 5% placebo-adjusted weight loss in adult patients with obesity or overweight.

Sarah Gray, PharmD, GAICD, discussed her experience as a pharmacist who added nutrition counseling to her clinical expertise.

Sarah Gray, PharmD, GAICD, known as the Nutrition Pharmacist, joined Drug Topics to discuss her experience with patients looking to begin healthier lifestyles at the start of a new year.

MET-097i from Metsera demonstrated substantial reductions in mean body weight in patients with obesity or overweight who did not have type 2 diabetes.

Jennifer Clements, PharmD, BCACP, BC-ADM, BCPS, CDCES, FADCES, FCCP, discussed the benefits of tirzepatide compared with semaglutide.

US News & World Report nutrition experts detailed the best types of diets for maintaining patient health in 2025.

Check out this list of our top 5 most read obesity stories from the year 2024.

Zepbound from Eli Lilly is the first and only prescription medicine approved by the FDA for adults with obstructive sleep apnea and obesity.

Although the drug fell short of its 25% expected weight loss, results are still promising for people with overweight or obesity.

Researchers assessed the importance of a nutritious diet and the role pharmacists play in providing dietary management services.

The drugs were compared over a 72-week study period.

In a recent clinical trial, weekly semaglutide demonstrated promise as a nonsurgical, nonopioid intervention for reducing knee osteoarthritis pain.

Analyzing copayments and coverage plans for popular weight-loss drugs in the US, researchers addressed the cost-effectiveness of GLP-1 medications for treating obesity.

Without financial incentives, some senators expressed concerns that pharmaceutical research and development would stall.

Senators sought to uncover why prices of Novo Nordisk’s GLP-1 receptor agonist semaglutide are significantly higher in the US compared with countries in Europe.

In the US, Ozempic costs more than 9 times what it does in Germany, while Wegovy is more than 4.5 times more expensive than in Denmark.