Nonopioid Pain Management

The new approval is the first nonopioid option for moderate to severe acute pain in adults.

Pharmacists are well positioned to screen for diversion, monitor for opioid use disorder, and educate patients on opioid-related risks.

There were no statistically significant differences between cognitive behavioral therapy and mindfulness-based therapy in reducing the dosage for chronic lower back pain.

Traditional approaches have typically relied on oral medications, which can expose the entire body to potentially harmful adverse effects.

According to poison control data, many children aged 0 to 17 experience toxicity from over-the-counter analgesics like ibuprofen and acetaminophen.

As pharmacists move away from opioids in pain management, researchers present the use of supplemental OTC products to assist patients’ acute pain.

Cebranopadol met its primary endpoint of reduction in pain intensity as measured by the Pain Numeric Rating Scale (NRS) area under the curve from 2 through 48 hours.

In a third installment of our interview series with Chris Robinson, MD, PhD, we looked at the future of pain management and emerging technologies being used for treatment.

In a search for new treatment and prevention strategies for pain in patients with fibromyalgia, researchers explored bioavailable nutraceuticals and phytochemicals like polyphenols.

Chris Robinson, MD, PhD, joined Drug Topics to discuss the importance of education in newly explored technologies for the treatment of pain.

Researchers investigated the pharmacological management of chronic orofacial pain and provided guidance on its proper treatment.

Physician with expertise in pain research discussed emerging technologies in the future of pain medicine and how they must be adapted to improve patient outcomes.

Patients with musculoskeletal pain were treated with cryotherapy spray to assess its use in providing immediate and sustained pain relief.

Researchers investigate the effects of subanesthetic doses of esketamine for the treatment of pain and cognition in patients undergoing surgery.

A discussion on the new nonopioid selective NaV1.8 pain signal inhibitor with Madison Irwin, PharmD, BCPS.

For patients with atopic dermatitis reporting moderate-to-severe scratching, researchers explored the efficacy of an AI-enabled wearable sensor with closed-loop haptic feedback.

Cardiovascular health is known to be associated with the probability of having active or developing migraine in the future.

Researchers conducted a review of clinical studies to better understand non-oral drugs for the treatment of pain related to herpes zoster.

Researchers asked adults with chronic pain and physicians their opinions on cannabis regulations.

Reducing the number of opioid prescriptions for patients with lower back pain did not result in an increased use of other, risky pain medications.

Assessing the management of chronic low back pain, researchers compared outcomes of healthy lifestyle care with current guideline-recommended care.

A recent study found that edible or smoked cannabis use predicted little variability in pain relief.

Tocilizumab-anoh is the biosimilar formulation for ACTEMRA, a medication used to treat rheumatoid arthritis, COVID-19, and other diseases.

The decision makes the selective NaV1.8 pain signal inhibitor the first new class of medicine to treat acute pain in over 20 years.

Researchers analyzed liveborn infant data from January 2020 to June 2024 to determine prevalence, cause, and treatment strategies for pain among preterm infants.

A supratherapeutic dose of 1000 ug cebranopadol was significantly less likeable compared to 40 mg oxycodone when crushed and taken intranasally.

Researchers conducted a literature review of patients’ clinical experiences with using secukinumab to treat psoriatic arthritis.

Cebranopadol is a first-in-class investigational therapy that targets the nociceptin/orphanin FQ receptor and the µ-opioid receptor.

A combination of ibuprofen and acetaminophen was found to be superior to hydrocodone and acetaminophen in managing pain after impacted mandibular third-molar extraction surgery.

XG005 from Xgene Pharmaceutical is a novel, non-opioid chemical entity that targets anti-nociceptive and anti-neuropathic pain pathways.