HIV

Among the drugs presented, Biktarvy and lenacapavir, teropavimab, and zinlirvimab (LTZ) demonstrate rates of suppression of HIV, and vesatolimod is well tolerated.

Additional data shows that an investigational drug, given every 4 months with Apretude, kept viral levels suppressed for patients who were already on stable treatment.

These findings are shared as late-breaking data at the 32nd Conference on Retroviruses and Opportunistic Infections (CROI) being held in San Francisco, California.

A PDUFA target action date for the PrEP therapy has been set for June 19, 2025.

A tour of modern antiretroviral and pre-exposure prophylaxis therapies included the latest updates in HIV management and prevention.

In the most recent episode of Over the Counter, Jay Holloway, PharmD, AAHIVP, discussed advancements in HIV, especially regarding the role of pharmacists.

Jay Holloway, PharmD, AAHIVP, Pharmacist with the AIDS Healthcare Foundation, joined Drug Topics to discuss the role pharmacists play in providing care for people with HIV.

Jay Holloway, PharmD, AAHIVP, Pharmacist with the AIDS Healthcare Foundation, discussed the ongoing developments impacting patients with HIV and their prescription drugs.

Cassandra Esperant, PharmD, AAHIVP, discussed the ups and downs of her career journey as a clinical HIV pharmacist.

The data from PURPOSE 2 will be published in The New England Journal of Medicine.

Cassandra Esperant, PharmD, AAHIVP, leverages her expertise as a clinical pharmacist to advocate for the well-being of individuals with HIV.

Analyzing outcomes from the COVID-19, influenza, and pneumococcal vaccines, researchers explored the effectiveness and patient hesitancy surrounding each vaccine.

The first-line B/F/TAF regiment was evaluated in Hispanic/Latino patients, as well as in those with chronic kidney disease.

Gilead said data from the study will support global regulatory filings that the company plans to begin by the end of the year.

Full efficacy and safety results for the phase 3 PURPOSE 1 trial were announced by Gilead at AIDS 2024.

PASO DOBLE is the largest head-to-head, phase 4 randomized clinical trial comparing DTG/3TC and BIC/FTC/TAF in patients with HIV.

The theme of this year’s National HIV Testing Day encourages individuals to self-test for HIV as a means of demonstrating their compassion for themselves.

Check out these top featured stories from Drug Topics in June 2024.

Rilpivirine (Edurant Ped) effectively suppresses the HIV-1 virus in pediatric patients with HIV-1 RNA less than or equal to 100,000 copies/mL in combination with other antiretroviral therapies.

The new approval is supported by the phase 3 Study 4030, which evaluated the efficacy, safety, and tolerability profile of Biktarvy in a broad range of people with HIV-1 with or without pre-existing NRTI resistance, including those with the M184V/I resistance.

Participants of a recent study who received automated text messaging and monitoring, as well as peer support and coaching, increased PrEP uptake from 11% to over 20%.

Study results highlight the potential of blood-based markers in understanding neurological conditions.

Abacavir/dolutegravir/lamivudine is a fixed-dose combination containing two nucleoside reverse transcriptase inhibitors (NRTIs) and integrase strand transfer inhibitor (INSTI).

Previously hepatitis B vaccines have offered lower levels of protection for people living with HIV. New research indicates that a 3-dose series could offer much better protection.

Researchers speculate that the disparities among those with private insurance coverage may reflect differences in overcoming hurdles to access, such as prior authorization.

Lenacapavir was approved with the FDA's Breakthrough Therapy Designation.

About 40% of people monkeypox also had HIV, according to a CDC study that included almost 2000 monkeypox cases in the United States that occurred during the first 2 months of the outbreak.

The risk of breakthrough was higher in people living with HIV regardless of CD4 count or HIV viral suppression, according to findings reported by researchers at Johns Hopkins.

PrEP is an effective way to fight HIV transmission, and more pharmacies are providing this important service.

Results address the concern that COVID-19 vaccination might not be effective among those living with HIV.