Oncology

A substantial collection of evidence indicates that the fallopian tube serves as the primary site of origin for a large portion of high-grade serous ovarian cancers.

A recent study being presented at the American College of Cardiology Latin America 2023 conference found the prevalence of cardiotoxicity among patients with breast cancer undergoing chemotherapy was 11.94%.

Findings showed that alternative to conventional follow-up resulted in a higher 3-year overall survival rate.

Nearly 25% of people “have vitamin D blood levels that are too low or inadequate for bone and overall health,” according to the NIH.

Black patients experience worse survival outcomes and exhibit more aggressive forms of the disease compared with White patients.

Wildfire smoke is a considerable contributor to air pollution, with wildfire smoke exposure consistently associated with respiratory morbidity including lung cancer risk.

An mHealth app for early detection of skin cancers was followed by an increase in the number of claims for premalignancies.

Quizartinib (Vanflyta) is an oral inhibitor of FLT3, and it specifically targets FLT3-ITD mutations, which drive cancer growth and contribute to increased risk of relapse and shorter overall survival.

A recent study determined over 12,000 screenings would need to be done to identify 1 case of melanoma in racial and ethnic minority populations.

A minimum dose of 3.4 to 3.6 minutes of vigorous intermittent lifestyle physical activity per day was associated with a 17% to 18% reduction in total incident cancer risk.

A new study found that 25%-46% of esophageal adenocarcinomas in patients with newly diagnosed Barrett’s esophagus were categorized as post-endoscopy esophageal adenocarcinoma.

Radiation therapy was associated with the largest increase, compared to chemotherapy or endocrine therapies.

Other research has suggested that SNRIs can lead to DNA damage, which the investigators said may be the avenue by which the drugs affect lung cancer risk.

Immune-checkpoint inhibitors were comparably safe and effective in patients with chronic hepatitis B or occult hepatitis B infection.

Although excessive use can lead to fatigue, alerts can help proactively identify and prevent drug interactions.

Carboplatin and cisplatin are currently in short supply.

The median annual cost for new oncology medicines launched in 2022 was $260,000, up from $63,534 10 years ago, an IQVIA report finds.

Overall survival rates for various cancers differed by race.

Knowledge gaps exist around the timing of pneumonitis onset in patients treated with checkpoint inhibitors.

The combination of Lynparza and abiraterone reduced the risk of disease progression or death by 76% vs. abiraterone alone in patients with BRCA-mutated metastatic castration-resistant prostate cancer.

A short supply of cisplatin and carboplatin is forcing health care providers to find less effective alternative treatments.

From compounding to cleaning, oncology pharmacy technicians take on key responsibilities in infusion centers.

From explaining how medications work and should be taken to reviewing potential adverse effects and financial details, pharmacists are crucial resources for patients undergoing treatment for skin cancer.

A new survey found that neither generation is particularly good at maintaining healthy sun habits, and have low skin cancer awareness.

Approximately 8000 to 9000 U.S. patients would be eligible for this combination, intended for patients with locally advanced or metastatic urothelial cancer (la/mUC).

Off-label drug combinations are increasingly being used in cancer treatments, but there is the potential for overlapping or additive toxicities, explained a speaker at the 2023 HOPA Annual Conference.

During a session at the 2023 HOPA Annual Conference, Rebecca Champion, PharmD, BCOP, highlighted new therapies in the market for hematologic malignancies with a focus on bispecific antibodies and chimeric antigen receptor T-cell therapies.