
Patients with SCD are more vulnerable to hospitalization due, in part, to SCD’s impact on the spleen, which filters infections in the blood and is a crucial organ for the immune system.

Patients with SCD are more vulnerable to hospitalization due, in part, to SCD’s impact on the spleen, which filters infections in the blood and is a crucial organ for the immune system.

Study authors theorized that the reduced effect could be due to disease-related or immunosuppressive treatment factors.

Receiving the vaccine during pregnancy is cited as crucial for both confronting disproportionate infant vulnerability and easing the disease burden for new and expecting mothers.

Black patients experience worse survival outcomes and exhibit more aggressive forms of the disease compared with White patients.