Latebreakers: CMS clarifies National Provider Identifier (NPI) rule as deadline looms
April 16th 2007Less than two months before a May 23 deadline, CMS has finally offered public recognition that many healthcare providers may not be ready for the changeover to the National Provider Identifier (NPI) standards.
Of two minds: New research finds atypicals are just a modest improvement in schizophrenia treatment
April 16th 2007Antipsychotic agents have long been integral to the management of schizophrenia. First-generation, "conventional" antipsychotics are high-affinity antagonists of dopamine D2 receptors. Although they are effective against antipsychotic symptoms, they are also associated with a high rate of neurologic adverse effects. Such effects include tardive dyskinesia and extrapyramidal symptoms (EPS).
The pain game: With safety concerns slowing traditional treatments, new options are filling the void
April 16th 2007Debilitating pain-affecting millions of Americans-was often alleviated by traditional nonsteroidal anti-inflammatory drugs (NSAIDs) and COX-2 inhibitors. But the appeal of these once-popular drugs is declining due to safety concerns.
Infection surveillance software can save lives
April 16th 2007As many as 100,000 patients die every year from hospital-acquired infections. It doesn't have to be that way. HAIs are eminently preventable. Tools exist that can significantly lower HAI mortality and morbidity rates and reduce an associated $6 billion in excess annual health costs.
Controversy continues to surround generic insulin
April 16th 2007Diabetes is a deadly, common and costly disease, so the debate about biogenerics is ardent when it concerns insulin. The drug is expensive and indispensable, and scientists agree that creating generic insulin is simpler than creating most other potential biologic equivalents.
Clinical twisters: Assessing risk to QT interval
April 16th 2007A 70-year-old woman, T.R., has been transferred from an extended care nursing facility to your hospital with symptoms of fever, dyspnea with respiratory difficulty, cough, and sputum production. Her current medications include methadone 200 mg/ day (pain syndrome), risperidone (Risperdal, Janssen) 2 mg twice daily, digoxin 0.125 mg daily, and furosemide 20 mg twice daily.
Health Mart: Drug Topics' 2007 Chain of the Year
April 16th 2007In the early 1990s, when Health Mart was owned by regional wholesale distributor FoxMeyer, it was little more than a franchise tallying 800 stores. Now it is a pharmacy franchise logging 1,280 stores. The chain has experienced nearly a 400% growth rate over the past 10 months.
FDA draft covers adverse event reports to IRBs
April 16th 2007The FDA announced the availability of a draft guidance designed to assist the research community in interpreting requirements for submitting reports of unanticipated problems such as certain adverse events reports to Institutional Review Board (IRB).