
|Articles|September 13, 2007
Rocephin PI updated to reflect calcium interaction
Ceftriaxone prescribing information updated to warn of calcium interaction
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Revisions have been made to the label of ceftriaxone (Rocephin, Roche) to include warning of the potential risk of crystallization when the antibiotic is used concomitantly with calcium or calcium-containing solutions or products. The update advises healthcare professionals to avoid coadministration, including with continuous infusions of calcium-containing parenterals such as TPN, even via different sites. Ceftriaxone and calcium solutions should not be administered within 48 hours of each other in any patient, regardless of age.
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