Clinical

Articles

Preliminary findings suggest patients with multiple sclerosis who are taking cladribine can mount and maintain effective vaccine responses. 

Study: Patients Receiving MS Therapy Achieve Response to Common Vaccines 

Pharmacists can advise patients on how to control symptoms and reduce exacerbations. 

A Primer on Atopic Dermatitis

The intramuscular administration of peginterferon beta-1a (Plegridy; Biogen) offers patients with relapsing multiple sclerosis a new treatment option. 

FDA OKs New Intramuscular Administration for Multiple Sclerosis Therapy

Voclosporin (Lupkynis; Aurinia Pharmaceuticals) is indicated in combination with a background immunosuppressive therapy for the treatment of active lupus nephritis in adults. 

FDA Approves Oral Therapy for Lupus Nephritis

Here are some of the top-read FDA approvals covered by Drug Topics® from this year.

Top FDA Approvals of 2020

Prefilled syringes have been the way that many children with juvenile idiopathic arthritis get their methotrexate. A pilot study examines if prefilled pens might be a better option.

Journal Club: Prefilled Pen to Deliver Methotrexate to Children With JIA

Pharmacists can play an integral role in educating patients about nutrition and lifestyle factors. 

Nutrition Counseling Tips for Patients With Autoimmune Conditions

Results of 2 recent studies suggested a higher risk of developing osteoporosis in patients with inflammatory bowel disease.

Inflammatory Bowel Disease May Increase Risk of Osteoporosis

Kevin W. Chamberlin, PharmD, is associate clinical professor and assistant department head, pharmacy practice, University of Connecticut School of Pharmacy, Storrs, Conn.

An overview of the use of satralizumab-mwge (Enspryng; Genentech) in neuromyelitis optica spectrum disorder (NMOSD).

Satralizumab-mwge for Neuromyelitis Optica Spectrum Disorder in Adults

Two lots of the thyroid tablets are being recalled after testing found the lots to be subpotent. 

Acella Recalls 2 Lots of Thyroid Medication for Subpotency

Higher cumulative exposure to systemic antibiotic therapy may be associated with a greater risk of new-onset inflammatory bowel disease.

Antibiotics Linked to Higher Risk of Inflammatory Bowel Disease

Pharmacists can play an important role in educating patients about autoimmune drugs to prevent medication errors.

Prevent Medication Errors in Autoimmune Disease

Levodopa/carbidopa is currently the gold standard for controlling motor symptoms associated with Parkinson disease. 

Opicapone Can Help Treat Patients Experiencing “Off” Episodes With Parkinson Disease

Ofatumumab (Kesimpta; Novartis) is the first and only self-administered, targeted B-cell therapy for the treatment of relapsing multiple sclerosis. 

FDA OKs Ofatumumab for Treatment of Relapsing Multiple Sclerosis

The therapy received fast track designation and was approved in just over 1 year. 

FDA Approves Satralizumab-mwge for Treatment of Rare Autoimmune Disease

Frieda Wiley, PharmD, BCGP, is a writer and pharmacist. 

A Kawasaki-like inflammatory disease has affected children who have coronavirus disease 2019.

Investigators Find COVID-19 Connection in Vasculitis

The data from a new study has shown that investigational, long-acting injectable cabotegravir boasted a 66% higher efficacy than daily oral pills in preventing HIV-1.

Investigational Long-Acting Injectable Cabotegravir Shows Superior Efficacy Over Daily Oral PrEP

A new study found increased plaque buildup levels in women with HIV who also suffered from persistent depression and stress. 

Women With HIV and Persistent Depression May Experience Greater Risk for Heart Disease

In studies presented this month at the European E-Congress of Rheumatology 2020, investigators revealed positive findings for the infliximab biosimilar CT-P13 (Inflectra, Remsima), which is developed by Celltrion of Incheon, Republic of Korea.


Studies Reveal Positive Results for Infliximab Biosimilar

A recent analysis showed a surge in prescription fills for hydroxychloroquine/chloroquine, likely due to off-label prescribing for coronavirus disease 2019. 

Autoimmune Diseases