Cannabidiol Effectiveness in Seizure Disorders


Trevor Resnick, MD, an epileptologist with special qualifications in pediatric neurology at the Nicklaus Children's Hospital, gives an overview of Cannabidiol and its efficacy for patients with Lennox-Gastaut syndrome and Dravet syndrome.


Trevor Resnick, MD: Cannabidiol is a derivative of cannabis, and we don't really know the mechanism of action for Cannabidiol. It may be linked to the g-receptor protein or the -- we don't know. Nevertheless, it has been demonstrated to be effective in patients with Lennox-Gastaut syndrome and in patients with Dravet syndrome. And it's actually approved for seizures associated with those two syndromes. And, I think it's approved for above 2-years of age. And the effectiveness of Cannabidiol was gratifying in those 2 syndromes, and it's approved for those 2 syndromes.

And the major side-effects are fatigue, sleepiness, diaherra. And another, not specifically a side-effect, but it does have interaction with some medications that are commonly used for both those syndromes.

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