The pain game: With safety concerns slowing traditional treatments, new options are filling the void
April 16th 2007Debilitating pain-affecting millions of Americans-was often alleviated by traditional nonsteroidal anti-inflammatory drugs (NSAIDs) and COX-2 inhibitors. But the appeal of these once-popular drugs is declining due to safety concerns.
Valve risk leads to withdrawal of pergolide (Permax, Valiant)
April 16th 2007Two high-quality reports in the New England Journal of Medicine confirming the risk of valvulopathy with the use of pergolide (Permax, Valiant) have led the FDA to remove the drug from the U.S. market. Two generic forms of the drug, made by Teva and Par Pharmaceuticals, will also be withdrawn.