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The final nail has been driven into the homocysteine-lowering coffin as a means to prevent recurrent coronary events. The results from the homocysteine-lowering arm of the SEARCH (Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine) trial found no benefit to folic acid combined with vitamin B12

Neither vitamin C nor vitamin E is effective for primary prevention of cardiovascular events in men, according to results of the Physician’s Health Study II, which evaluated the risk and benefits of both vitamins as well as a multivitamin in preventing cardiovascular disease and cancer. Results relating to cancer prevention will be presented November 17 at the Frontiers in Cancer Prevention Research conference.

Rosuvastatin treatment of patients with better than average lipid profiles but with elevated high-sensitivity C-reactive protein (hsCRP) resulted in a 44% relative risk reduction in cardiovascular events and a 20% reduction in all-cause mortality, reports Paul Ridker, MD (pictured), lead investigator for the JUPITER Trial Study Group. JUPITER was an investigator-initiated trial sponsored by AstraZeneca.

Johns Hopkins researchers have identified five proteins that may serve as an early warning of impending myocardial infarction (MI) in patients presenting to emergency rooms with ischemia symptoms. A blood test to detect all, or a subset of these proteins, could be used by physicians and paramedics in the 12- to 24-hour window before ischemia causes tissue damage or death.

Barr Pharmaceuticals has received final FDA approval for galantamine, its generic version of Ortho McNeil Janssen's Razadyne ER, for the treatment of mild to moderate dementia of the Alzheimer's type.

Letters: November 10, 2008

Pharmacists speak out about drug kiosks, tobacco sales, fee for service, and e-prescribing.

The pharmacy school at University of Maryland is building an expansion to open in fall 2010. It will feature a dispensing lab, research facilities, lecture halls, and a distance-learning facility.

A San Francisco judge denied Philip Morris' request for a temporary restraining order against the ban on pharmacy sales of tobacco products. The ban will affect 52 of 54 Walgreens as well as other chain pharmacies such as Rite-Aid and Longs.

The Joint Commission's anticoagulant safety goal goes into effect Jan. 1, 2009. Physicians, pharmacists, and nurses at health-care systems around the country are collaborating to improve best practices and to put more stringent measures in place.

The U.S. Food and Drug Administration is notifying health care professionals and patients that Tyco Healthcare Group LP (Covidien) is recalling one lot of ReliOn sterile, single-use, disposable, hypodermic syringes with permanently affixed hypodermic needles due to possible mislabeling. The use of these syringes may lead to patients receiving an overdose of as much as 2.5 times the intended dose, which may lead to hypoglycemia, serious health consequences, and even death.

APhA taps new VP, CEO

The American Pharmacists Association (APhA) recently named its new executive vice president and CEO. The decision was made on the heels of the announcement earlier in 2008 that its current CEO is stepping down. Read on to find out what direction APhA will head.

The Pharmacy Museum Foundation of Texas is donating an antique collection worth $250,000 to the University of the Incarnate Word (UIW) Feik School of Pharmacy.