Feature|Articles|August 3, 2026

A Brief History of Vaccines: Smallpox, Polio, and Beyond

Centuries of vaccine science saved more lives than any other intervention, and pharmacists matter now more than ever.

For centuries, people have searched for ways to protect one another from deadly infectious disease. What began with risky, informal experiments against smallpox eventually grew into a scientific discipline responsible for saving more human lives than any other medical intervention in history.1