All News

In a novel collaboration with PBM giant CVS Caremark and its specialty pharmacy Generation Health, PGXL Laboratories will use its expertise in anticoagulants to improve the quality of patient care through pharmacogenetic testing, physician education, and drug-specific software programs.

Genetic testing in oncology

While genetic testing can identify patients who will be nonresponsive to certain drug therapies, it can also suggest other drugs as treatment options that might work. These may include pharmaceuticals not usually considered for treatment of a particular cancer.

Infections with the deadly methicillin-resistant Staphylococcus aureus (MRSA) bacteria contracted in hospitals and other healthcare settings have declined 28% over a 4-year period, according to a new Centers for Disease Control and Prevention (CDC) study of about 15 million people.

In the first week of August, the Senate unanimously passed the Secure and Responsible Drug Disposal Act (S. 3397) to provide for take-back disposal of controlled substances by legitimate users-patients.

Calcium supplementation is associated with an increased risk of myocardial infarction (MI), according to a meta-analysis published online July 29 in BMJ and reported by HealthDay News.

Novartis Vaccines has started shipping the FDA-approved seasonal influenza vaccine Fluvirin to U.S. customers ahead of the 2010&endash;2011 season, allowing healthcare practitioners to initiate protection of their patients well in advance.

Certain lots of Advair Diskus (fluticasone propionate and salmeterol inhalation powder) inhalers that were stolen from a GlaxoSmithKline (GSK) distribution warehouse near Richmond, Va., in August 2009 have recently been found in some pharmacies, according to FDA.

FDA has approved Tribenzor (olmesartan medoxomil, amlodipine, hydrochlorothiazide), a new three-in-one combination product taken once daily for the treatment of hypertension in patients who are not adequately controlled on any 2 of the following antihypertensive drug classes: angiotensin receptor blockers, calcium channel blockers, and diuretics, according to Daiichi Sankyo Inc.

Patients taking newer antiepileptic drugs (AEDs) that are associated with a high risk of depression may have an elevated risk of self-harm or suicidal behavior, but other groups of AEDs do not appear to carry the same risk, according to research published in the July 27 issue of Neurology and reported in HealthDay News.

Oral antidiabetic (OAD) agents generally result in a maximum 1.5% drop in hemoglobin (Hb) A1C levels, with sulfonylureas and thiazolidinediones having a slightly more beneficial effect than other classes of oral agents, according to research published in the August issue of Diabetes Care and reported by HealthDay News.

Investigational combination treatment with sustained-release (SR) naltrexone and bupropion (Contrave, Orexigen Therapeutics) combined with lifestyle modification, appears effective in helping people lose 5% or more of their excess body weight, according to research published online July 30 in The Lancet and reported by HealthDay News.

With so many best-selling name-brand drugs coming off patent over the next few years, the market for generics should expand markedly. In Drug Topics' special generics supplement, pharmacists from around the country offer their views.

The generic market is likely to remain very strong between now and 2015, but the combination of healthcare reform and a lack of significant drugs coming off patent means that the outlook between 2015 and 2020 is murkier.

There are some big names among the brand drugs that have recently come off patent and joined the burgeoning generics market.

In a recent survey by Medco Health Solutions Inc., only 66% of 1,092 patients with insurance surveyed "agreed that a generic drug is the same as the brand-name medication - many patients are still not comfortable using a generic and others still consider brand-name drugs to be superior."

Pharmacy technology 2010

The latest pharmacy technologies include IVR, telepharmacy, cell-phone-based automatic refill reminders, a compact robotic dispenser, remote dispensing, and CPOE pharmacy management.

Use of bar-code technology is widespread in the general retail environment. Its advantages have not yet been fully exploited in the hospital and community-pharmacy settings.

With many pharmacists approaching retirement, positions are opening up. For professionals tasked with greater responsibility and longer working hours, greener pastures have an undeniable appeal. In this business climate, how can employers hold onto their pharmacy professionals?

Pharmacists are in a good position to tell patients that sand, water, snow, and clouds reflect and intensify the sun's rays, causing unsuspected sun damage, even in shade, and that protecting skin from sun damage should be incorporated into a daily routine.

Summer brings picnics, hikes, and trips to the water, along with sunburn, bug bites, and dry, itchy skin. For all that exposed skin, manufacturers offer several new skin-care aids.