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Warning of Lucentis stroke risk issued
According to a letter issued to healthcare providers by Genentech, maker of ranibizumab (Lucentis), use of the therapy may be associated with an increased risk of stroke, especially in patients who have previously had a stroke. Clinical trial data, collected after following patients an average of 230 days after starting treatment, showed a 1.2% incidence of stroke in patients given a 0.5-mg injection of ranibizumab compared with a 0.3% incidence for those receiving a 0.3-mg injection. The letter said the risk was higher for patients in the study who had already had a stroke. Ranibizumab is approved for treating wet age-related macular degeneration.
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Pharmaceutical Compounding, Storage of Faricimab Preserves Stability, Binding Properties
November 28th 2023Maintaining the structure and function of antibody biologics like faricimab is critical for their administration via intravitreal injection (IVI), a common treatment approach for retinal diseases.
