News|Articles|February 13, 2019

Ultomiris for Paroxysmal Nocturnal Hemoglobinuria

Author(s)Drew Boxler

ULTOMIRIS (ravulizumab-cwvz , Alexion Pharmaceuticals, Inc.)

Indications: treatment of adult patients with paroxysmal nocturnal hemoglobinuria

Dosage: intravenous infusion only

  • 40 kg ≤ X< 60 kg – 2,400mg leading, 3,000 mg maintenance

  • 60kg ≤ X < 100kg – 2,700mg leading, 3,300mg maintenance

  • 100kg ≤  X – 3,000mg leading, 3,600 maintenance

Contraindications: patients with unresolved Neisseria Meningitidis infection.

 

​Click here for more prescribing information

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Continuous Glucose Monitoring: What's New in 2025?
On-Demand Webinar

Continuous Glucose Monitoring: What's New in 2025?

1.0 Credit / Endocrinology, Diabetes & Metabolism

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Improving the Care of Persons Living With Diabetes Using CGM Devices (Pharmacy Technician Credit)
On-Demand Virtual Symposium

Improving the Care of Persons Living With Diabetes Using CGM Devices (Pharmacy Technician Credit)

1.5 Credits / Endocrinology, Diabetes & Metabolism

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Advancing Stroke Prevention: The Pharmacist’s Role in Implementing the 2024 Guidelines
Online Article

Advancing Stroke Prevention: The Pharmacist’s Role in Implementing the 2024 Guidelines

1.0 Credit / Cardiology

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The Role of IV Iron in Resolving Iron Deficiency in Heart Failure
On-Demand Webinar

The Role of IV Iron in Resolving Iron Deficiency in Heart Failure

1.0 Credit / Cardiology, General Pharmacy

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From Guidelines to Practice: The Pharmacist’s Role in Chronic Heart Failure Therapy Optimization
On-Demand Webinar

From Guidelines to Practice: The Pharmacist’s Role in Chronic Heart Failure Therapy Optimization

1.5 Credits / Cardiology

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Advances and Innovations in Hypertrophic Cardiomyopathy Management: A Focus on New and Emerging Therapies
On-Demand Webinar

Advances and Innovations in Hypertrophic Cardiomyopathy Management: A Focus on New and Emerging Therapies

1.5 Credits / Cardiology

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Mastering Hyperlipidemia Management: Enhancing Adherence and Expanding Nonstatin Therapy Options
On-Demand Virtual Symposium

Mastering Hyperlipidemia Management: Enhancing Adherence and Expanding Nonstatin Therapy Options

1.5 Credit / Cardiology

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Discipline Decoded: Navigating Pharmacy Law and Disciplinary Cases (Pharmacy Technician Credit)
On-Demand Virtual Symposium

Discipline Decoded: Navigating Pharmacy Law and Disciplinary Cases (Pharmacy Technician Credit)

1.0 Credit / General Pharmacy, Law

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Beyond the Prescription: Tackling Social Isolation for Better Health (Pharmacy Technician Credit)
On-Demand Virtual Symposium

Beyond the Prescription: Tackling Social Isolation for Better Health (Pharmacy Technician Credit)

0.5 Credit / General Pharmacy

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Beyond the Prescription: Tackling Social Isolation for Better Health
On-Demand Virtual Symposium

Beyond the Prescription: Tackling Social Isolation for Better Health

0.5 Credit / General Pharmacy

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Evaluating the Role of Pharmacists in Utilizing Potassium-Competitive Acid Blockers for Acid Peptic Disorders
On-Demand Virtual Symposium

Evaluating the Role of Pharmacists in Utilizing Potassium-Competitive Acid Blockers for Acid Peptic Disorders

1.0 Credits / Gastroenterology

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Understanding and Personalizing Chronic Obstructive Pulmonary Disease Diagnosis and Treatment
On-Demand Virtual Symposium

Understanding and Personalizing Chronic Obstructive Pulmonary Disease Diagnosis and Treatment

1.0 Credit / Infectious Disease, Immunization

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Balancing Pain Management and Opioid Use Disorder: Recognition, Treatment, and Compassionate Communication in Pharmacy Practice
On-Demand Virtual Symposium

Balancing Pain Management and Opioid Use Disorder: Recognition, Treatment, and Compassionate Communication in Pharmacy Practice

1.0 Credit / Pain Management

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Respiratory Syncytial Virus Disease Prevention in Adults: The Pharmacist’s Role in Improving Vaccine Uptake
On-Demand Virtual Symposium

Respiratory Syncytial Virus Disease Prevention in Adults: The Pharmacist’s Role in Improving Vaccine Uptake

1.0 Credit / Immunization

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Discipline Decoded: Navigating Pharmacy Law and Disciplinary Cases
On-Demand Virtual Symposium

Discipline Decoded: Navigating Pharmacy Law and Disciplinary Cases

1.0 Credit / General Pharmacy, Law

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Leveraging Novel Therapies to Transform Demodex Blepharitis Care (Pharmacy Technician Credit)
On-Demand Webinar

Leveraging Novel Therapies to Transform Demodex Blepharitis Care (Pharmacy Technician Credit)

1.5 Credit / Ophthalmology/Optometry

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Leveraging Novel Therapies to Transform Demodex Blepharitis Care
On-Demand Webinar

Leveraging Novel Therapies to Transform Demodex Blepharitis Care

1.5 Credit / Ophthalmology/Optometry

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Advancing Multiple Sclerosis Treatment: Exploring Evolving Therapies and Patient-Centered Approaches
On-Demand Virtual Symposium

Advancing Multiple Sclerosis Treatment: Exploring Evolving Therapies and Patient-Centered Approaches

1.5 Credits / Neurology

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New and Emerging Therapies for the Management of Narcolepsy: A Guide to Patient-Centered Care
On-Demand Virtual Symposium

New and Emerging Therapies for the Management of Narcolepsy: A Guide to Patient-Centered Care

1.5 Credits / Neurology

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Navigating the Complexity of Migraine: A Multimodal Approach to Acute Treatment
On-Demand Virtual Symposium

Navigating the Complexity of Migraine: A Multimodal Approach to Acute Treatment

1.5 Credits / Neurology

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Identifying and Personalizing Iron Deficiency Anemia Treatment in Patients With Cancer
On-Demand Webinar

Identifying and Personalizing Iron Deficiency Anemia Treatment in Patients With Cancer

1.0 Credit / Oncology, General Pharmacy

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Managing Iron Replacement Therapies for Patients With Inflammatory Bowel Disease
On-Demand Webinar

Managing Iron Replacement Therapies for Patients With Inflammatory Bowel Disease

1.0 Credit / Gastroenterology, General Pharmacy

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Iron Deficiency Anemia Treatment Considerations in Women’s Health
On-Demand Webinar

Iron Deficiency Anemia Treatment Considerations in Women’s Health

1.0 Credit / Women's Health, General Pharmacy

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The Changing Paradigm in Pain Management and Supporting Access to Novel Therapies
On-Demand Webinar

The Changing Paradigm in Pain Management and Supporting Access to Novel Therapies

1.0 Credit / Pain Management/Opioids

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The Expanding Therapeutic Landscape in IgA Nephropathy: A Case-Based Exploration of Optimized Patient Outcomes
On-Demand Webinar

The Expanding Therapeutic Landscape in IgA Nephropathy: A Case-Based Exploration of Optimized Patient Outcomes

1.0 Credit / Immunology, Nephrology

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Exploring ATTR Phenotypes and Identifying Appropriate Opportunities for Pharmacists to Intervene
On-Demand Webinar

Exploring ATTR Phenotypes and Identifying Appropriate Opportunities for Pharmacists to Intervene

1.0 Credits / Cardiology, Nephrology

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Personalizing Treatment in Relapsed/Refractory Multiple Myeloma: The Evolving Role of Antibody-Drug Conjugates and Bispecific Antibodies
On-Demand Webinar

Personalizing Treatment in Relapsed/Refractory Multiple Myeloma: The Evolving Role of Antibody-Drug Conjugates and Bispecific Antibodies

1.0 Credits / Hematologic Cancer, Oncology

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Advances in Castration-Sensitive Prostate Cancer: A Pharmacist's Approach to Optimize Novel Antiandrogen Therapies
On-Demand Webinar

Advances in Castration-Sensitive Prostate Cancer: A Pharmacist's Approach to Optimize Novel Antiandrogen Therapies

1.0 Credits / Men's Health, Oncology, Urology

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Adapting to Advances in EGFR-Positive Non-Small Cell Lung Cancer Treatment: Critical Insights for Oncology Pharmacists
On-Demand Virtual Symposium

Adapting to Advances in EGFR-Positive Non-Small Cell Lung Cancer Treatment: Critical Insights for Oncology Pharmacists

1.0 Credits / Lung Cancer, Oncology

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Securing the Supply Chain: The Pharmacists’ Role in DSCSA Compliance
Online Article

Securing the Supply Chain: The Pharmacists’ Role in DSCSA Compliance

1.0 Credit / Law

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Expanding the Role of Long-Acting Injectables in Optimizing Schizophrenia Management
On-Demand Webinar

Expanding the Role of Long-Acting Injectables in Optimizing Schizophrenia Management

1.5 Credits / Psychiatry

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VMAT2 Inhibitors for Long-Term Success in Tardive Dyskinesia
On-Demand Webinar

VMAT2 Inhibitors for Long-Term Success in Tardive Dyskinesia

1.5 Credits / Neurology, Psychiatry

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Shifting Perspectives in Treatment-Resistant Depression: Novel Therapies and Patient-Centered Care
On-Demand Webinar

Shifting Perspectives in Treatment-Resistant Depression: Novel Therapies and Patient-Centered Care

1.5 Credits / Psychiatry

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Navigating Adverse Effects in HR+/HER2-Negative Metastatic Breast Cancer: Tailored Management Plans and Pharmacist Interventions for Improved Outcomes
On-Demand Webinar

Navigating Adverse Effects in HR+/HER2-Negative Metastatic Breast Cancer: Tailored Management Plans and Pharmacist Interventions for Improved Outcomes

1.0 Credits / Breast Cancer, Oncology, Women's Health

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Bridging Knowledge Gaps in HR+/HER2– Early-Stage Breast Cancer
On-Demand Webinar

Bridging Knowledge Gaps in HR+/HER2– Early-Stage Breast Cancer

0.75 Credits / Breast Cancer, Oncology, Women's Health

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Optimizing Therapy in HR+/HER2-Negative Metastatic Breast Cancer: Navigating Novel Treatments and Personalized Care
On-Demand Webinar

Optimizing Therapy in HR+/HER2-Negative Metastatic Breast Cancer: Navigating Novel Treatments and Personalized Care

1.0 Credits / Breast Cancer, Oncology, Women's Health

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Exploring Oncolytic Viruses in Melanoma: Pharmacist-Led Approaches for Safe Integration
On-Demand Virtual Symposium

Exploring Oncolytic Viruses in Melanoma: Pharmacist-Led Approaches for Safe Integration

1.0 Credits / Oncology

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Opioids, Pain Management, and Substance Use Disorder: A Practical Overview
On-Demand Webinar

Opioids, Pain Management, and Substance Use Disorder: A Practical Overview

2.0 Credits / Pain Management/Opioids

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