The technical transition requires a departure from the relatively simple, instantaneous world of pharmacy benefit manager claims based on national drug codes.3 Instead, medical billing utilizes a complex system of current procedural terminology and health care common procedure coding system codes that describe exactly what clinical service was provided.1,3,4
To navigate these waters, pharmacists must distinguish between hospital-based and physician-based billing models. In hospital-owned facilities, dual charges for professional and facility fees are common, though pharmacists often face barriers to independent billing in these settings.5 Conversely, physician-based settings may offer better positioning for pharmacists to generate revenue through state-specific or payer policies.
The industry is also pivoting toward value-based care, a model that rewards providers for the quality and effectiveness of their care rather than just the volume of visits. This transition creates deeper partnerships between pharmacists and patients, particularly in managing chronic conditions and closing gaps in care.5,6
Success in this new frontier requires proactive credentialing and engagement with clinically integrated networks to manage payer relationships. Pharmacists are encouraged to utilize resources such as pharmacy profiles to demonstrate their clinical qualifications to insurance carriers.1
Watch Our Medical Billing Decoded Series
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In the first installment of the series, Jennifer Griffin, PharmD, MS, clinical pharmacist for Harps Food Stores, and Dwayne Jones, BSPharm, regional pharmacy supervisor and clinical program director for Harps Food Stores, share how a small regional chain successfully built and scaled clinical services across 39 pharmacy locations—without adding extra staff.
Although the learning curve for medical billing is steep and requires mastery of diagnosis codes and payer manuals, the accessibility of pharmacists remains their greatest asset. With 90% of Americans living near a pharmacy and public trust remaining high after the successful delivery of millions of COVID-19 vaccines, pharmacists are uniquely positioned to unlock sustainable revenue through direct patient care.1,3
The profession must embrace its clinical scope of license now rather than waiting for a federal provider status mandate that has been stalled in committees for years.1
“I always have said that we will stand together or fall alone. The big issue we have in pharmacy is we all want to be in our own organizations, and then we don't look out for each other, and then we fall,” concluded Wolff. “But we'll go into this together and make sure all of you know how to do medical billing, make sure all of you know to take care of your patients, document and get paid for it, and [it] will go a long way.”
READ MORE: APhA Annual Meeting and Exposition
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REFERENCES
1. Wolff T. How I met your modifier: medical billing for pharmacy professionals. Presented at: American Pharmacists Association 2026 Annual Meeting and Exposition; March 27-30, 2024; Los Angeles, CA.
2. Blacketer M. Final physician fee schedule expands billing opportunities for pharmacists. ASCP. November 10, 2025. Accessed April 1, 2026. https://www.ascp.com/news/714280/Final-Physician-Fee-Schedule-Expands-Billing-Opportunities-for-Pharmacists.htm
3. Polo M. Pharmacy medical billing 101: What is It and how to master your pharmacy’s revenue cycle management. NCDS Medical Billing and Practice Management. Accessed April 1, 2026. https://www.ncdsinc.com/pharmacy-medical-billing-101-what-is-it-and-how-to-master-your-pharmacys-revenue-cycle-management/
4. Billing guidance for pharmacists’ professional and patient care services. NCPDP. June 2018. Accessed April 1, 2026. https://www.ncpdp.org/NCPDP/media/pdf/WhitePaper/Billing-Guidance-for-Pharmacists-Professional-and-Patient-Care-Services-White-Paper.pdf
5. Hospital-based billing and physician-based billing. APhA. November 26, 2025. Accessed April 1, 2026. https://www.pharmacist.com/Blogs/CEO-Blog/Article/Hospital-based-billing-and-physician-based-billing
6. Understanding the shift to value-based care for pharmacy, part I. XiFin. January 25, 2023. Accessed April 1, 2026. https://www.xifin.com/resource/blog-post/value-based-care-pharmacy-part-1/