OR WAIT 15 SECS
Nilotinib capsules approved for Philadelphia chromosome-positive chronic myelogenous leukemia (CML).
Exerting its effect by targeting the Bcr-Abl protein, which is produced only by cells containing the abnormal Philadelphia (Ph) chromosome, nilotinib capsules (Tasigna, Novartis) have been granted an accelerated approval for the treatment of Ph+ chronic myelogenous leukemia (CML) in adult patients resistant or intolerant to prior therapy that included imatinib (Gleevec, Novartis). During clinical trials, nilotinib produced responses in 40% of Ph+ CML patients who were resistant or intolerant to prior therapy. According to Novartis, the new drug will be available within days of its approval.
To see more Hot off the Press news articles, click here.
To go to the Drug Topics homepage, click here.