OTC Products: Smoking Cessation

A pharmacist's guidance is essential when selecting effective OTC smoking cessation medications that provide relief from nicotine withdrawal symptoms and cravings. Because the path to quitting is often difficult, pharmacists play a vital role by assessing a patient's habit—specifically, whether they are a heavy smoker (first cigarette within 30 minutes of waking) or a light smoker (first smoke after 30 minutes)—to recommend the appropriate nicotine strength. This professional consultation helps patients navigate the various forms of nicotine replacement therapy (NRT) while checking for potential interactions and preexisting health conditions, such as heart disease or high blood pressure, which may require a physician’s advice before beginning treatment.

NRT products deliver therapeutic nicotine to help calm withdrawal symptoms and reduce the urge to smoke, effectively doubling a patient's chances of success compared with quitting cold turkey. Committing to a quit plan can help individuals reclaim years of healthy living and better manage the mental stress associated with withdrawal. Whether patients prefer the oral satisfaction of gum or lozenges or the long-lasting relief from an extended-release patch, these products offer scientifically backed methods to help users move toward a smoke-free life.

Best for On-the-Go Craving Relief

CVS Sugar Free Nicotine Gum, Original

Nicotine polacrilex 2 mg

Distributed by CVS Pharmacy

CVS Sugar Free Nicotine Gum provides long-lasting relief from cravings while keeping the user's mouth busy, which is a key benefit for many smokers during the quitting process. The 2-mg strength is typically indicated for individuals who smoke their first cigarette more than 30 minutes after waking.

• This sugar-free stop-smoking aid helps to control nicotine intake and ease the transition away from cigarettes.
• When purchasing this or similar products at CVS, federal law or security protocols may require a valid ID for certain regulated pharmacy items.
• Users are generally advised to use 1 piece every 1 to 2 hours for the first 6 weeks of their quit program.
• The gum form is ideal for "on-the-go energy" and provides a dual benefit of relief and behavioral replacement, according to the package.

Best for Discreet, Fast-Acting Relief

Nicorette 4 mg Nicotine Lozenges Mint

Nicotine polacrilex 4 mg

Manufactured by Haleon

Nicorette’s solid, mint-flavored lozenges slowly dissolve in the mouth, releasing therapeutic nicotine to satisfy cravings discreetly. The 4-mg strength is indicated for individuals who have their first cigarette within 30 minutes of waking up.

• These lozenges provide long-lasting relief from cravings and continue to work even after they have fully dissolved.
• The recommended 12-week schedule begins with 1 lozenge every 1 to 2 hours for weeks 1 through 6, gradually tapering off through week 12.
• For optimal results, users should allow the lozenge to dissolve slowly (approximately 20 to 30 minutes) and refrain from eating or drinking for 15 minutes before and during use.
• To prevent adverse effects such as hiccups, heartburn, or nausea, users should not exceed 5 lozenges in 6 hours or 20 lozenges per day.

Best for All-Day Craving Prevention

NicoDerm CQ Nicotine

Patches Nicotine, 21 mg

Manufactured by Haleon

NicoDerm CQ patches have Extended Release SmartControl Technology to provide 24-hour craving relief by steadily releasing nicotine through the skin throughout the day. The clear patch can be worn under clothing, making it a convenient option for all-day efficacy.

• The 21-mg patch is typically step 1 in a 3-step quit process, depending on the individual’s initial nicotine habits.
• Unlike oral NRT forms, the patch requires only once-a-day application, making it simpler for users.
• The product helps prevent the urge to smoke before it starts by maintaining a consistent level of nicotine in the bloodstream.
• For maximum effectiveness, it is recommended that individuals use the patch as part of a comprehensive program that includes behavioral support.