|Articles|July 21, 2008

FDA retracts hold on alvimopan

However, partner in drug development deal may be backing out.

The U.S. Food & Drug Administration revoked a clinical hold on Entereg, according to Adolor Corp. The drug is under development for treatment of bowel dysfunction in individuals on opioid therapy. Despite this news, partner GlaxoSmithKline is considering backing out of the development arrangement.

Alvimopan (Entereg) received FDA approval in May for the treatment of post-operative ileus. The following month, FDA issued a hold on further studies of the drug pending submission and requested data analysis.

To see more Daily News articles, click here.

To go to the Drug Topics homepage, .

Pharmacy practice is always changing. Stay ahead of the curve with the Drug Topics newsletter and get the latest drug information, industry trends, and patient care tips.

FDA retracts hold on alvimopan

Related Content

Wicked Good Cardiometabolic Chat: Essential 2026 AACE Diabetes Updates for Pharmacists

Q&A: Pharmacists Can Address ADA Standards Across All Settings

Executive Order Calls for Realignment of Childhood Vaccines

Heat and Older Adults: What Pharmacists Need to Know

Pneumococcal Vaccination at 50 Years Old Can Improve Outcomes

Latest CME

Improving the Care of Persons Living With Diabetes Using CGM Devices

Advancements With CGM Integrations: Insulin Pumps, Connected Pens, and Ketone Monitoring

Demystifying CGM: Addressing Frequently Asked Questions and Key Insights

A Deep Dive Into CGM Data

Demystifying CGM: Addressing Frequently Asked Questions and Key Insights (Pharmacy Technician Credit)

Continuous Glucose Monitoring: What's New in 2025?

A Deep Dive Into CGM Data (Pharmacy Technician Credit)

Improving the Care of Persons Living With Diabetes Using CGM Devices (Pharmacy Technician Credit)

Advancements With CGM Integrations: Insulin Pumps, Connected Pens, and Ketone Monitoring (Pharmacy Technician Credit)

Continuous Glucose Monitoring: What's New in 2025? (Pharmacy Technician)

Advancing Stroke Prevention: The Pharmacist’s Role in Implementing the 2024 Guidelines

The Role of IV Iron in Resolving Iron Deficiency in Heart Failure

Advances and Innovations in Hypertrophic Cardiomyopathy Management: A Focus on New and Emerging Therapies

From Guidelines to Practice: The Pharmacist’s Role in Chronic Heart Failure Therapy Optimization

Mastering Hyperlipidemia Management: Enhancing Adherence and Expanding Nonstatin Therapy Options

Understanding and Personalizing Chronic Obstructive Pulmonary Disease Diagnosis and Treatment

Respiratory Syncytial Virus Disease Prevention in Adults: The Pharmacist’s Role in Improving Vaccine Uptake

Beyond the Prescription: Tackling Social Isolation for Better Health

Balancing Pain Management and Opioid Use Disorder: Recognition, Treatment, and Compassionate Communication in Pharmacy Practice

Beyond the Prescription: Tackling Social Isolation for Better Health (Pharmacy Technician Credit)

Discipline Decoded: Navigating Pharmacy Law and Disciplinary Cases (Pharmacy Technician Credit)

Empowering Pharmacists in Travel Medicine: Enhancing Patient Care Through Vaccination, Prevention, and Education

Evaluating the Role of Pharmacists in Utilizing Potassium-Competitive Acid Blockers for Acid Peptic Disorders

Empowering Pharmacists in Travel Medicine: Enhancing Patient Care Through Vaccination, Prevention, and Education (Pharmacy Technician Credit)

Discipline Decoded: Navigating Pharmacy Law and Disciplinary Cases

Leveraging Novel Therapies to Transform Demodex Blepharitis Care (Pharmacy Technician Credit)

Leveraging Novel Therapies to Transform Demodex Blepharitis Care

Oncology Pharmacists Connect 2026

Advancing Multiple Sclerosis Treatment: Exploring Evolving Therapies and Patient-Centered Approaches

New and Emerging Therapies for the Management of Narcolepsy: A Guide to Patient-Centered Care

Navigating the Complexity of Migraine: A Multimodal Approach to Acute Treatment

Identifying and Personalizing Iron Deficiency Anemia Treatment in Patients With Cancer

Managing Iron Replacement Therapies for Patients With Inflammatory Bowel Disease

Exploring ATTR Phenotypes and Identifying Appropriate Opportunities for Pharmacists to Intervene

The Impact of Pharmacists and Pharmacy Technicians in Recognizing and Responding to Human Trafficking (Pharmacist Credit)

The Impact of Pharmacists and Pharmacy Technicians in Recognizing and Responding to Human Trafficking (Pharmacy Technician Credit)

Iron Deficiency Anemia Treatment Considerations in Women’s Health

The Changing Paradigm in Pain Management and Supporting Access to Novel Therapies

The Expanding Therapeutic Landscape in IgA Nephropathy: A Case-Based Exploration of Optimized Patient Outcomes

Personalizing Treatment in Relapsed/Refractory Multiple Myeloma: The Evolving Role of Antibody-Drug Conjugates and Bispecific Antibodies

Advances in Castration-Sensitive Prostate Cancer: A Pharmacist's Approach to Optimize Novel Antiandrogen Therapies

Adapting to Advances in EGFR-Positive Non-Small Cell Lung Cancer Treatment: Critical Insights for Oncology Pharmacists

Securing the Supply Chain: The Pharmacists’ Role in DSCSA Compliance

Expanding the Role of Long-Acting Injectables in Optimizing Schizophrenia Management

VMAT2 Inhibitors for Long-Term Success in Tardive Dyskinesia

Shifting Perspectives in Treatment-Resistant Depression: Novel Therapies and Patient-Centered Care

Navigating Adverse Effects in HR+/HER2-Negative Metastatic Breast Cancer: Tailored Management Plans and Pharmacist Interventions for Improved Outcomes

Bridging Knowledge Gaps in HR+/HER2– Early-Stage Breast Cancer

Optimizing Therapy in HR+/HER2-Negative Metastatic Breast Cancer: Navigating Novel Treatments and Personalized Care

Optimizing HER2-Directed Therapy in Metastatic Breast Cancer: From HER2-Positive to HER2-Ultralow

Shaping the Future of Generalized Myasthenia Gravis Management: A Focus on Novel Treatment Approaches

Expert Insights on the Horizon of HER2-Directed Therapy

Breaking Barriers in Asthma Care: Exploring the Role of Type 2 Inflammation and Biologic Therapies

Type 2 Inflammation in Focus: Advancing Pediatric Atopic Dermatitis Care With Biologic Therapies

From Flares to Freedom: Navigating the Journey of Patients With Chronic Spontaneous Urticaria With Next-Generation Therapies

Chronic Obstructive Pulmonary Disease and Inflammation: Practical Approaches to Integrating Biologic Therapy

Understanding Type 2 Inflammation and Its Role Across Various Immune-Related Diseases

Trending on Drug Topics

Executive Order Calls for Realignment of Childhood Vaccines

The Prodigious PBM Pivot: How Supply Chain Entities Will Move Forward After CAA 2026

Q&A: Pharmacists Can Address ADA Standards Across All Settings

Embedded Pharmacists Are Vital Yet Underutilized in Diabetes Care

Heat and Older Adults: What Pharmacists Need to Know