FDA: Cardiac monitoring critical in MS patients taking mitoxantrone

Because many multiple sclerosis patients taking mitoxantrone (Novantrone, Immunex) are not having their cardiac functions monitored as recommended, the Food & Drug Administration just sent an alert out to health professionals to remind them of the importance of this task. In addition, the agency issued a new recommendation. All MS patients who have finished treatment with mitoxantrone should receive yearly quantitative left ventricular ejection fraction (LVEF) evaluation to detect late-occurring cardiac toxicity.

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