6 Ways to Boost Profitability in Your Pharmacy

Independent pharmacies are sitting on untapped revenue—and most of it is hiding in plain sight. From wholesaler pricing gaps and real-time benefit tools to patient engagement technology and over-the-counter (OTC) suggestive selling, the strategies that separate thriving independents from those that struggle are less about reinventing operations and more about activating the systems already at their fingertips.

As reimbursement models shift away from script volume and toward health outcomes, pharmacy owners who treat their software ecosystem as a profit engine—rather than just a dispensing tool—are finding meaningful advantages in an increasingly competitive market.

With more than 25 years of health care technology leadership through a platform that serves thousands of pharmacies nationwide, Ketan Mehta, CEO and president of PrimeRx, brings a practitioner-level perspective to one of the most pressing challenges facing independent operators today in his Total Pharmacy Solutions Summit Spring 2026 keynote presentation.

His session opens with a candid look at how the pharmacy technology landscape has changed over the past few decades. Mehta argues that the old, modularized approach to pharmacy software is giving way to a true ecosystem model; one where purchasing, inventory management, audits, copay collection, and patient engagement are no longer siloed but deeply interconnected.

From there, the session moves into real-time prescription benefit tools, showing how a benefits investigation can be run before a prescription is even filled—surfacing formulary status, copay tiers, and prior authorization requirements the moment an electronic script arrives. Patient engagement is another focal point, with Mehta making the case that app-less, text-initiated communication has become the new standard for keeping patients loyal, informed, and able to manage their own care around the clock.

Whether you're a single-location owner or managing a growing pharmacy group, this session offers concrete, data-backed strategies geared toward financial sustainability. Watch the full presentation to see the real-world savings figures, workflow demonstrations, and platform models Mehta walked through live.

Explore more of our coverage from the Total Pharmacy Solutions Summit Spring 2026: Growth Prescribed.