May 2nd 2024
A siloed approach to care can worsen patient outcomes, but collaboration between one health system specialty pharmacy and a manufacturer led to better patient care.
ASHP takes a hard line on specialty residencies
July 11th 2005In a show of solidarity, ASHP persuaded more than 500 of its members to sign a petition urging the Centers for Medicare & Medicaid Services to restore pass-through Medicare funding for specialized pharmacy residency programs. ASHP joins the American College of Clinical Pharmacy (AACP) in asking CMS to revise the proposed rule. The ongoing battle between ASHP and CMS that has been brewing for two years was one of the highlights of the 2005 ASHP Summer Meeting in Boston last month.
Clinical Twisters: Managing ESRD following MI
June 20th 2005A 50-year-old man, C.C., has been hospitalized for acute myocardial infarction (MI) and a stent was placed. C.C. also has end-stage renal disease (ESRD) and is on three-times-weekly hemodialysis. Post-MI, his physician has prescribed metoprolol 50 mg b.i.d., ramipril (Altace, King Pharmaceuticals) 10 mg q.d., atorvastatin (Lipitor, Pfizer) 10 mg q.d., nitroglycerin 0.4 mg sublingual, warfarin 5 mg q.d., and clopidogrel (Plavix, Sanofi-Aventis) 75 mg q.d. C.C.'s predialysis lab values today are parathyroid hormone=405 pg/dl, corrected Ca=10.3 mg, P=5.7 mg, Ca x P 58.71 mg 2 /dl 2. Dialysate calcium concentration is 2.4 mEq/L. C.C.'s nephrologist is evaluating whether to change his preexisting regimen of calcium acetate and calcitriol. What do you suggest?
Advances in targeted therapy stand out at ASCO
June 20th 2005At the recent annual meeting of the American Society of Clinical Oncology (ASCO), some 25,000 cancer specialists from around the world came to Orlando, Fla., to consider the latest advances in cancer care, treatment, and prevention. Novel targeted therapies for major cancers abounded, as did improvements in quality of life for patients suffering adverse effects from conventional therapy. Here are some highlights
Customized strategy drives this bar-code vendor
June 20th 2005Despite all the hype on bar-code technology, less than 5% of the nation's hospitals have installed a bedside bar-code system, even though there is mounting evidence that the technology combined with a comprehensive medication management system can substantially reduce medication errors and improve overall patient safety.
Cardiovascular disease: Deadly for dialysis patients
June 6th 2005Current treatment of dialysis patients with cardiovascular disease (CVD) is suboptimal, according to newly published guidelines by a work group of the National Kidney Foundation (NKF). Lack of evidence of treatment efficacy and exclusion of dialysis patients from major CVD clinical trials may have contributed to the problem.
Getting the physician on board with CPOE
May 15th 2005The hardest part of installing a CPOE (computerized physician order entry) system may be getting the physicians to use it. A hospital can have chosen good software and hardware and may have all the technology in place, but no system will work until physicians start to use it.
USP Drug Safety Review: Errors related to JCAHO's National Patient Safety Goals
May 15th 2005In 2002, JCAHO formed the Sentinel Event Alert Advisory Group to help develop the first set of National Patient Safety Goals (NPSGs) that were put into effect on Jan. 1, 2003. NPSGs and their accompanying requirements represent specific actions that JCAHO-accredited organizations are expected to take in order to prevent medical errors such as miscommunication among caregivers, unsafe use of infusion pumps, and medication mix-ups. USP has studied medication error data findings reported to the MEDMARX program in relation to the following 2005 NPSGs
Activist pushes for access to hospital infection rates
May 15th 2005In 2002, with data supplied by the British National Health Service, newspapers in England began publishing the names of hospitals with high infection rates. By 2004, every hospital in Great Britain was required to display its infection rate in a prominent place where patients could see it.
Transplant group calls for pharmacists on team
May 15th 2005Pharmacists are gaining new support in the organ transplantation world. UNOS, the United Network for Organ Sharing, is encouraging all transplant centers to include at least one clinical R.Ph. on each transplant team. UNOS coordinates organ donation and transplantation specialists nationwide.
FDA approves label changes for Natrecor
May 15th 2005Scios Inc., a Johnson & Johnson company, has changed its package labeling to add data about deaths associated with its heart failure drug nesiritide (Natrecor) after studies in prominent medical journals raised questions about an increased risk of fatal renal problems. The Food & Drug Administration-approved label change, which stops short of an outright warning, indicated that in clinical trials 5.3% of the patients treated with nesiritide died, compared with 4.3% who took other agents, including diuretics and intravenous nitroglycerin. However, the new label states that the data might not be statistically significant because of the small number of patients involved.
Pharmacists can do more for heart failure patients
May 15th 2005Are hospitalized heart failure patients getting adequate discharge instructions, such as counseling on diet, exercise, medication management, and smoking cessation? Not according to the results of a new study released by the world's largest heart failure registry-ADHERE (Acute Decompensated Heart Failure National Registry).
More states require med-error reports
May 15th 2005Does your state require the reporting of medication errors? If the answer is No, get ready for a change. Twenty-three states, including California, Florida, New York, and other major hospital population centers, already mandate med-error reports. Another six states are actively considering legislation, according to on-line publisher NETSCAN, based in Falls Church, Va.
What is bioidentical HRT and is there evidence to support its use?
May 2nd 2005A: Findings from the Womens Health Initiative (WHD) and other studies offered important information about the risks and benefits of long-term menopausal therapy. As a result, it is currently recommended that HRT be used only for the treatment of moderate to severe menopausal symptoms (vasomotor symptoms, symptoms of vulvar and vaginal atrophy) at the lowest effective dose and for the shortest duration of time consistent with a woman's individual treatment goals and risks. Results from these trials have prompted many women to seek alternatives to conventional HRT. One such alternative is bioidentical hormone replacement therapy (BHRT).
Pegfilgrastim benefits moderate-risk patients, too
May 2nd 2005A study of 928 breast cancer patients showed that those receiving first and subsequent cycle administration of pegfilgrastim (Neulasta, Amgen) had a whopping 94% decline in the incidence of febrile neutropenia, a 93% decline in hospitalizations, and an 80% drop in intravenous anti-infective use. The patients had been considered at moderate risk for neutropenic complications.
Two hospitals' run-in with the JCAHO offers warning for all
May 2nd 2005A California hospital recently lost its accreditation from the Joint Commission on Accreditation of Healthcare Organizations, and another one is at risk of losing it. In both cases, medication-related problems accounted for part of the reason for their predicament. Their experience could signal a tougher approach by JCAHO.
CMS proposes new rules for participating in Medicare
May 2nd 2005Health-system pharmacists are taking a wait-and-see attitude about proposed rule changes for hospitals' conditions of participation (CoPs) in Medicare that were announced recently by the Centers for Medicare & Medicaid Services. When the feds first proposed these rules eight years ago, it provoked a firestorm of protest from R.Ph.s.
JAMA report questions CPOE safety
April 18th 2005Perhaps nothing is as professionally frustrating to today's health-system pharmacists as the gap between the promise and reality of computerized physician order entry (CPOE). Concern may have risen to a new level in March with publication of a report in the Journal of the American Medical Association that said CPOE could cause as many medication errors as it prevents. Add that to a growing awareness among R.Ph.s that many physicians hate the systems and the fact that most hospitals can't afford them, and CPOE's promise of improved patient safety seems a dream.
Hospira/Bridge Medical deal draws positive reaction
April 18th 2005The improper programming of an intravenous pump is among the most common mistakes made at the patient's bedside. A decimal point in the wrong place could be catastrophic. But what if a physician's order were electronically transmitted from a point-of-care medication management system directly to the infusion device at the bedside, with a safety check feature that ensures the pump is programmed properly and consistent with the physician's order?
Pharmacists shrug as hospital charges are posted
April 18th 2005A growing move by states and health plans nationwide to post hospital charges for public scrutiny is eliciting yawns from pharmacists. "We don't expect any impact on pharmacy," said Pharmacy Society of Wisconsin spokesman Tom Engels. State law requires disclosure of hospital charges through a program called Wisconsin Pricepoint, run by the Wisconsin Hospital Association.
CDC offers guide to states on reporting infection rates
April 18th 2005The Centers for Disease Control & Prevention recently released detailed recommendations to state health departments that are considering mandatory public reporting of healthcare-associated infections (HAIs). "HAIs are a major public health problem in the United States," said Patrick Brennan, M.D., chairman of the CDC's Healthcare Infection Control Practices Advisory Committee (HICPAC), which wrote the document.
Clinical Twisters: Treating epilepsy in pregnancy
April 18th 2005A 22-year-old woman, L.N., arrived at your emergency department after a "spell." Based on her symptoms and EEG findings, her physician has diagnosed the spell as a complex partial seizure that generalized to a secondary tonic-clonic seizure. L.N.'s neurological exam, physical exam, complete blood count, serum glucose, electrolytes, drug/alcohol screen, and lumber puncture were normal. However, while in the hospital, she experienced a second seizure, prompting her physician to consider antiepileptic drug (AED) therapy. Because L.N. is two months pregnant, her doctor requests a pharmacist consult. What do you recommend?
Cardiology show highlights antiplatelet agent, COX-2 risks
April 18th 2005The always high-interest Late Breaking Clinical Trials at the Annual Scientific Session of the American College of Cardiology, held in Orlando, Fla., were particularly notable this year. First, they included an unprecedented three individual sessions on the antiplatelet agent Plavix (clopidogrel, Sanofi-Aventis). Second, justifying the plunge to lower and lower LDL-cholesterol (LDL-C) targets, they included strong results for a trial of 80 mg of atorvastatin (Lipitor, Pfizer), and, finally, they featured a session with conflicting messages on the risks of COX-2 inhibitors.