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The FDA recently approved tiotropium (Spiriva HandiHaler, Pfizer/Boehringer-Ingelheim) inhalation powder for the long-term, once-daily, maintenance treatment of bronchospasm associated with COPD, including bronchitis and emphysema. In the airways, tiotropium inhibits muscarinic (M3) receptors at the smooth muscle, leading to bronchodilation. The manufacturer anticipates that tiotropium will be available in pharmacies by mid-year.

States are up in the air about their discount card programs following the passage of the Medicare drug benefit legislation, which has a provision for an Rx card program

Clinicians can now treat patients with bipolar depression using the first drug approved in the U.S. for this indication. The FDA recently approved olanzapine/fluoxetine (Symbyax, Eli Lilly) for the treatment of depressive episodes associated with bipolar disorder. Symbyax is currently available in pharmacies.

Following in the footsteps of Walgreens, CVS announced that it will not participate in future health plan contracts requiring refill scripts to be filled by mail order pharmacies.