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A key provision of the Affordable Care Act kicked in January 1 when Medicare beneficiaries who have Part D but don?t get the low-income subsidy ?Extra Help? began receiving a 50% discount under the Medicare Coverage Gap Discount Program on applicable drugs at point of sale. The following article explains how pharmacies should prepare.

Many serious or potentially fatal adverse reactions associated with new, targeted anti-cancer agents are not reported in the original published research on the drug, and they are not known to oncologists until years later when drug labels are updated, including boxed warnings, according to research published online in the Journal of Clinical Oncology, HealthDay News reported.

Patients who are newly treated with statin-fibrate concurrent therapy are slightly more likely to be hospitalized with rhabdomyolysis than those who take just one of the medications, according to research published in the American Journal of Cardiology, HealthDay News reported.

Many serious or potentially fatal adverse reactions associated with new, targeted anti-cancer agents are not reported in the original published research on the drug, and they are not known to oncologists until years later when drug labels are updated, including boxed warnings, according to research published online in the Journal of Clinical Oncology, HealthDay News reported.

State Medicaid programs could save $30 billion over the next decade by replacing fee for service pharmacy programs with managed care programs like those used in Medicare Part D, according to a new report on Medicaid pharmacy spending sponsored by the Pharmaceutical Care Management Association.

Patients who switch statins have lower persistence to therapy compared to those who don?t switch, according to a poster recently presented at the 45th midyear meeting of the American Society of Health-Systems Pharmacists.

In a multi-national, placebo-controlled, double-blind trial, the selective vitamin D receptor activator paricalcitol (Zemplar, Abbott Laboratories), at doses of 1 µg or 2 µg daily, can reduce albuminuria in patients with type 2 diabetes, who were already being treated with renin-angiotensin-aldosterone system inhibitors.

In research published in the October 1 issue of the American Journal of Cardiology, HealthDay News reported, metformin, either alone or in combination with sulfonylurea, appears to increase 1-year and long-term survival in patients with T2DM and CHF.

FDA has approved Gardasil (Merck) for the prevention of anal cancer and associated precancerous lesions due to human papillomavirus (HPV) types 6, 11, 16, and 18 in individuals aged 9 through 26 years.

Diagnostic testing, narcotics, and questionable treatment modalities appear to be overused for chronic neck pain, while effective treatments such as therapeutic exercise appear to be underused, according to a study in the November issue of Arthritis Care & Research, HealthDay News reported.