The anticholinergic drug tiotropium is more effective than the Β2-agonist salmeterol in preventing exacerbations in patients with moderate-to-very-severe chronic obstructive pulmonary disease, according to a multicenter European study published in the New England Journal of Medicine.
Patients with inflammatory rheumatic disease may need 2 doses of adjuvanted split influenza A vaccine to elicit the same antibody response as healthy individuals, reported a recent Swiss study published in Arthritis & Rheumatism.
Clopidogrel hypersensitivity, which affects 6% of patients, can be successfully treated using short-course corticosteroids and antihistamines without interrupting drug therapy, reported researchers at Jefferson Medical College in Philadelphia.
Combining angiotensin-converting-enzyme inhibitors with angiotensin-receptor blockers is associated with increased risk of adverse renal outcomes, according to a recent study published in the Canadian Medical Association Journal.
FDA said it wouldn't take action against compounding pharmacies that continue to supply 17 alpha hydroxyprogesterone caproate.
FDA recently approved vandetanib to treat patients with late-stage (metastic) medullary thyroid cancer who are ineligible for surgery and have a disease that is growing and causing symptoms.
FDA issued drug safety communications about a serious adverse effect associated with the use of over-the-counter benzocaine gels, sprays, and liquids applied to the throat and gums to reduce pain.
FDA has approved gabapentin enacarbil (Horizant Extended-Release Tablets, GlaxoSmithKline and XenoPort), a once-daily treatment for moderate-to-severe restless legs syndrome, also known as Ekbom disease. It is the first medication in its class to be approved for this condition.
The American Society of Health Systems Pharmacists recently published Anticoagulation Therapy: A Point-of-Care Guide for clinicians, pharmacists, and pharmacy residents.
The use of high-dose clopidogrel compared with use of standard-dose clopidogrel does not reduce the incidence of death from cardiovascular causes, nonfatal myocardial infarction, or stent thrombosis among patients with high on-treatment reactivity after percutaneous coronary intervention with drug-eluting stents, according to a recent multicenter study published in the Journal of the American Medical Association.
Antibiotic use is rising at Veterans Affairs medical facilities across the country, according to findings released at the annual meeting in Dallas of the Society for Healthcare Epidemiology of America.
Both the Food and Drug Administration and officials from a number of generic drug companies indicate they are in active talks on creating user fees to be paid by that industry to give the agency more resources to speed generics to the market, carry out inspections and other functions.
The American Pharmacists Association Foundation recently announced the first 25 healthcare organizations that will be participating in its Project IMPACT: Diabetes program.
Kathleen Jaeger has resigned as executive vice president and CEO of the National Community Pharmacists Association (NCPA) because she disagreed with NCPA executives about the organization's direction.
APP Pharmaceuticals Inc. in Schaumburg, Ill., recently recalled 5 lots of irinotecan hydrochloride injection, used to treat recurrent or progressive metastatic colorectal cancer. Greenstone LLC has recalled 1 lot of Citalopram, used to treat depression, because the bottles may contain finasteride.
Naproxen/esomeprazole magnesium (Vimovo, AstraZeneca and Pozen) 500/20-mg delayed-release tablets was generally well tolerated in osteoarthritis patients requiring daily NSAID therapy who were at risk for NSAID-associated ulcers, according to a study published in Current Medical Research & Opinion.
5α-reductase inhibitors may cause persistent erectile dysfunction, depression, and loss of libido, even after discontinuing use, in men being treated for systems of benign prostatic hyperplasia and androgenetic alopecia, according to a literature review published in The Journal of Sexual Medicine.
Patients with systemic lupus erythematosus are commonly nonadherent to therapy, according to a recent study published in Arthritis Care & Research.
Prescription Solutions, a pharmacy benefits manager and a UnitedHealth Group company in Irvine, Calif., recently launched an online service that speeds up approval of prior authorization requests.
The risk of fracture is unlikely in patients taking short-term, low-dose proton pump inhibitors, according to a review of available safety data by FDA.
Evidence supports metformin as a first-line agent to treat type 2 diabetes, according to a study in the online edition of the Annals of Internal Medicine.
While Purdue Pharma, the manufacturer of OxyContin, has offered the State of Florida $1 million for a pill mill database, the anticipated cost of sustaining the program may deter Florida Governor Rick Scott and other legislators from accepting the grant.
American Regent, a division of Luitpold Pharmaceuticals in Shirley, N.Y., recently recalled several lots of Dexamethasone Sodium Phosphate Injection and Sodium Chloride Injection because they may contain particulates.
Walgreens has acquired online retailer Drugstore.com Inc. for $409 million in cash.
Patients with diabetes who are more adherent to their therapy incur slightly lower healthcare costs, according to a recent study in the journal Health Services Research.
FDA recently released new medication guides and made revisions to a number of others. The following is a synopsis of FDA's actions.
Bartell Drugs is holding a "Health and Beauty Event," featuring health clinics, free beauty "mini-makeover" demonstrations and hair-styling tips, and product samplings ranging from cosmetics to specialty foods and candies.
The 2011 Health & Wellness Conference taking place April 3 to April 5 at the Omni Resort at ChampionsGate in Orlando, Fla., will give supermarket executives opportunities to collaborate with suppliers and service providers on ways to meet the wellness needs of consumers.
Weight-loss products that promise consumers quick and easy ways to shed pounds don't live up to their claims and, even worse, can cause serious harm, FDA has announced.
FDA has a new target in its continuing efforts to clean up pharmaceutical industry abuses: individual corporate officials. The most recent targets are the vice president of quality and the vice president of operations for OTC Products at McNeil Consumer Healthcare, a subsidiary of Johnson & Johnson.