Tzipora Lieder, RPh

There are an estimated 34.1 million adults with diabetes, accounting for 13% of all US adults and a staggering 26.8% of US adults aged 65 or older.

 Every day, patients with diabetes are in the aisles of local pharmacies in search of OTC products to help them with various symptoms, whether diabetes-related or not. What should pharmacists consider when helping these patients choose appropriate OTC products?

Patients with diabetes frequently come to the pharmacy in search of relief for peripheral neuropathy—but experts say pharmacists shouldn’t rush to recommend OTCs.

“[If I were] a community pharmacist, if somebody told me that they’re having pin and needles or tingling in their fingers or their toes, I’d actually recommend that they go back to their doctor because usually, that’s a sign that their diabetes is not under control,” said Candis M. Morello, PharmD, CDCES

, FCSHP, FASHP, professor of clinical pharmacy at UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences in La Jolla, California. Morello is director of the diabetes intense medical management clinic at the Veterans Affairs San Diego Healthcare System, where her team creates unique treatment protocols for very complex patients with type 2 diabetes.

According to Morello, when glycemic control is improved, diabetes complications, including peripheral neuropathy, are “absolutely reversible.” She found that this usually takes about 3 months using a multiprong approach, including diet, exercise, and drug therapy. In the interim, there is a place for OTC treatment for peripheral neuropathy.

Although the supplement α-lipoic acid has demonstrated positive effects on peripheral neuropathy, Morello is hesitant to recommend it to patients who are already taking a slew of oral prescription drugs. She prefers topical options, including capsaicin cream (0.075% 4 times daily, according to the American Academy of Neurology

Morello said patients should be cautioned to wash hands well—including under their nails—after using capsaicin cream to avoid accidentally getting it in their eyes. Lidocaine patches can be cut to fit the affected area and may be worn for up to 12 hours per day.

In considering the root cause of peripheral neuropathy, pharmacists should determine whether the patient is a smoker, as smoking can decrease blood flow to extremities and lead to nerve pain, noted Danielle Hambrick, PharmD, manager of a Walgreens pharmacy in downtown Chicago, Illinois. According to her, this symptom might be the impetus for patients with diabetes to quit smoking. Pharmacists can assist such patients in selecting smoking cessation aids, such as nicotine patches for long-term control and nicotine gum for breakthrough cravings.

“Ulcers, amputations, all of that is preventable,” Morello said, as long as patients look at their feet every single day and visit their physician at the first sign of a problem. Hambrick added that any sign of infection on the feet, such as an open wound, swelling, or fever, is a huge red flag and should be referred to the patient’s physician. 

OTC moisturizers are important in the prevention of foot problems. “If you have dry skin, you can get fissures, and bacteria and fungi love to invade and cause infection,” Morello explained. There are a variety of diabetic foot creams on the market; she recommends those containing urea or ammonium lactate. Hambrick pointed out that moisturizers should only be used on the tops and soles of feet, not between the toes, which could lead to fungal growth.

According to Hambrick, patients with diabetes should be educated about proper foot care. This includes always drying feet entirely after bathing and protecting feet by wearing socks in the house and shoes outside. Nail files are preferred for cutting toenails, but if clippers must be used, they should only be straight-edged, not curved, to avoid cutting the skin.

Although various vitamins and supplements are promoted for diabetes, there is limited data on their efficacy. In fact, supplements such as St. John’s wort, prickly pear cactus, aloe, and ginseng may interact with conventional diabetes drugs. Certainly, patients should not take dietary supplements in place of medications they have been prescribed for diabetes.

Studies have found that various vitamins play a role in glucose metabolism and the risk for diabetes and its complications, but there is not enough data to recommend routine supplementation in the general population with diabetes. An exception is vitamin B12 supplementation in patients with type 2 diabetes taking metformin. Patients should be encouraged to eat a varied diet to ensure sufficient vitamin intake.

Although the American Diabetes Association does not recommend routine multivitamins for patients with diabetes, Morello said that she and the dieticians she works with still recommend multivitamins because it can be difficult for patients to get all their nutrients solely from food sources.

Morello noted that patients who decide to take dietary supplements should be urged to choose only products that have been validated by a third party, such as the USP Dietary Supplement Verification Program or ConsumerLabs.com. “You just want to make sure that it was manufactured properly, that the amount and concentration that it says is in the bottle is actually in the bottle,” she said. “They’re spending valuable money, and we want to make sure they’re getting a product that actually contains what it says it does.”

Pharmacists should be mindful that patients seeking relief from cold and flu symptoms might also have diabetes. “Any patient that comes up with an over-the-counter question, there's always a chance they could [have] diabetes, so part of our counseling is making sure that we understand their pre-existing conditions,” said Hambrick. These patients should be counseled to steer clear of products containing sugar, including cold syrups and throat lozenges. Fortunately, there are still many options labeled sugar-free. They should also avoid products containing pseudoephedrine and other nasal decongestants, as they have been shown to increase blood glucose.

Hambrick noted that pharmacists should make sure patients with diabetes who have respiratory infections have an adequate supply of test strips. “Any time that a diabetic patient is ill, even if they're well controlled outside of that illness… they may have fluctuations with their blood glucose control, so they may need to test a little bit more often,” she said. These patients should also stock up on glucose tablets, she added, in case their blood sugar drops as a result of reduced appetite during illness.

According to Morello, for patients with diabetes complaining of constipation, psyllium is in excellent choice because it increases fiber intake and has been shown to decrease postprandial glucose concentrations.

Hambrick also stressed the importance of making sure patients with diabetes are adequately vaccinated. “With diabetes, your immune system is a little bit more compromised, and so those things like flu and pneumonia can be more severe,” she explained.

National diabetes statistics report, 2020. Centers for Disease Control and Prevention. Accessed December 7, 2020. 

https://www.diabetesresearch.org/file/national-diabetes-statistics-report-2020.pdf

AAN summary of evidence-based guideline for clinicians: Treatment of painful diabetic neuropathy. American Academy of Neurology. 2011. Accessed December 7, 2020.

Lidocaine transdermal patch. Medline Plus. Last updated March 15, 2016. Accessed December 7, 2020. 

https://medlineplus.gov/druginfo/meds/a603026.html

Diabetes and dietary supplements. National Center for Complementary and Integrative Health. Last updated May 2018. Accessed December 7, 2020. 

https://www.nccih.nih.gov/health/diabetes-and-dietary-supplements#:~:text=For%20example%2C%20chromium%20might%20help,diabetic%20neuropathy%20(nerve%20problems)

Valdés-Ramos R, Guadarrama-López AL, Martínez-Carrillo BE, Benítez-Arciniega AD. Vitamins and type 2 diabetes mellitus. 

. 2015;15(1):54-63. doi:10.2174/1871530314666141111103217

Articles

Over-the-counter product selection for patients with diabetes.

OTC Basics for Diabetes

The common cold may be considered a mild illness, but the runny nose, congestion, sneezing, cough, sore throat, headache, and other symptoms that come along with it can make people feel miserable. OTC products to treat upper respiratory infections are not a cure; at best, they provide temporary symptom relief. And yet, US consumers, desperate for reprieve from cold-related discomfort, spent more than $9 million last year on these products, according to the Consumer Healthcare Products Association.

Pharmacists play an important role in helping patients choose the appropriate OTC product based on patient characteristics and specific cold symptoms.

Although a plethora of OTC cough and cold medications are on phar- macy shelves, many of them are very similar. Most oral cold medications contain a combination of some or all of the following active ingredients:

Acetaminophen for relief of fever, sore throat, headache, and body aches

Decongestant phenylephrine for the relief of nasal congestion and runny nose

A first-generation antihistamine such as diphenhydramine, pheniramine, chlorpheniramine, or brompheniramine to reduce postnasal drip and help with sleep

Expectorant guaifenesin, which thins mucous secretions in respiratory passages so they can more easily be coughed up

Various products are available in tablet and/or syrup form. Some products, such as the Theraflu line, are available as packets of powder to be mixed into a hot drink—an added benefit because hydration, particularly with hot liquids, helps relieve cold symptoms. Nasal sprays are also an option; some nasal sprays contain decongestants such as oxymetazoline and phenylephrine, whereas saline nasal sprays serve to simply moisten the nasal passages to reduce irritation.

Although most combination drugs contain the same basic active ingredients, the number of different formulations on the shelf can be dizzying. Various brand names such as Mucinex, Robitussin, and DayQuil/ NyQuil each include several different products for relief of different symptoms. Descriptors can include “cough and cold,”“cold and flu,” and 

“cough and chest congestion”—sometimes with the word “severe” thrown in for good measure. Many of these are available in daytime and nighttime formulations, which are often packaged together in 1 box.

Mainstay ingredients for daytime cold and flu formulations are usually acetaminophen for fever and pain, phenylephrine for congestion, dextromethorphan for cough suppression, and guaifenesin for loosening secretions. Nighttime formulations for cold and flu typically omit guaifenesin, which can increase coughing, replacing it with dextromethorphan to suppress the cough or an antihistamine to promote drowsiness.

But never make assumptions about what’s in a particular product—the active ingredient or its dosage. For instance, although most combination products contain 325 mg of acetaminophen, some contain 650 mg. Dosages of dextromethorphan and guaifenesin also vary among products. Always check the label to be sure.

Although young children are notorious for frequently acquiring colds, they are not always the best candidates for treatment with OTC cold medicines. The FDA states that OTC cold medicines containing decongestants or antihistamines should not be used for children under aged 2 years, as they can cause serious adverse effects (AEs).

 The American Academy of Pediatrics (AAP) states that OTC cold medications should not be used in children under aged 4 years due to the risk of dangerous AEs; research has shown little benefit in children under aged 6 years.

Various products are designed for children, and most state on the packaging that they are for children aged 6 years and older. Children under 12 years of age should not take adult formulations of cough and cold medications, as the dosages may be inappropriate for them.

Caution parents buying pediatric products to keep them out of children’s reach, as accidental, unsupervised ingestion is a leading cause of AEs with these drugs.

For children who should not or prefer not to take OTC medications, the AAP recommends using cool mist humidifiers and administering saline nose drops, with a nasal aspirator for infants. Mentholated rubs can help soothe nighttime coughs, and single-ingredient acetaminophen or ibuprofen can be used for fever. There is evidence of honey providing relief for upper respiratory infections, and it is a safe option for children older than 1 year. Babies under 1 year of age should never be given honey due to risk of infant botulism. The AAP recommends half a teaspoon of honey for children aged 1 to 5 years, 1 teaspoon of honey for children aged 6 to 11 years, and 2 teaspoons of honey for children aged 12 years and older. Parents should be cautioned to brush the children’s teeth after taking honey before bedtime.

Patients’ awareness of what is contained in the OTC combination cold medications they’re taking is key to ensuring that they don’t accidentally overdose. They should especially be cautioned not to take more than 1 acetaminophen-containing product at a time, as acetaminophen overdose is a leading cause of acute liver failure. Although historically the maximum daily dose of acetaminophen was 4000 mg, the makers of Tylenol have lowered the maximum daily dose of single ingredient Tylenol to 3000 mg/day to promote safe use of acetaminophen products.

Since systemic and nasal decongestants work by causing vasoconstriction, they can worsen conditions such as hypertension, glaucoma, and benign prostatic hyperplasia. Patients with these conditions should be directed to formulations labeled “HBP” for high blood pressure or any other products that do not include decongestants.

Special care should be taken for patients taking monoamine oxidase (MAO) inhibitors, as they interact with several components of cough and cold medications. The use of decongestants with MAO inhibitors can cause hypertensive crisis, and dextromethorphan with MAO inhibitors can cause serotonin syndrome.

Patients should be reminded that nighttime formulations containing antihistamines cause drowsiness, so they should only be taken at bedtime—not before driving a vehicle or operating dangerous machinery.

Because there is so much variability between products, reading labels for cough and cold medications is essential to making proper patient-specific recommendations. For example, while Corcidin HBP and DayQuil HBP are similar in that neither contain decongestants, they do not contain the same ingredients; Corcidin HBP Cold & Flu contains acetaminophen and chlorpheniramine, whereas Dayquil HBP Cold & Flu contains acetaminophen and dextromethorphan.

Suffixes can be confusing. Although HBP in a drug name indicates that it is safe for patients with high blood pressure, the DM in some Robitussin products does not indicate that they are formulated for patients with diabetes mellitus. Instead, the DM in those products indicates that they contain dextromethorphan. Patients with diabetes should be directed to cough formulations that do not contain glucose, such as Diabetic Tussin. And the CF in other Robitussin products stands for cough/cold formulation, although those products also contain dextromethorphan.

Careful consideration may sometimes lead to the conclusion that patients might be better off with
a single ingredient drug, such as acetaminophen, ibuprofen, or a second-generation antihistamine.

OTC sales by category 2016-2019. Consumer Healthcare Products Association. Accessed September 10, 2020. 

Use caution when giving cough and cold products to kids. FDA. Updated February 8, 2018. Accessed September 10, 2020. 

https://www.fda.gov/drugs/special-features/use-caution-when-giving-cough-and-cold-products-kids

Caring for your child’s cold or flu. HealthyChildren. Updated April 19, 2019. Accessed September 10, 2020. 

https://www.healthychildren.org/English/safety-prevention/at-home/medication-safety/Pages/How-to-Manage-Colds-and-Flu.aspx

Green JL, Wang GS, Reynolds KM, et al. Safety profile of cough and cold medication use in pediatrics. 

Tylenol dosage for adults. Tylenol. Accessed September 10, 2020. https://www.tylenol.com/safety-dosing/usage/dosage-for-adults

Cold versus flu. CDC. Updated August 31, 2020. Accessed September 14, 2020. 

https://www.cdc.gov/flu/symptoms/coldflu.htm

Similarities and differences between flu and COVID-19. CDC. Updated August 31, 2020. Accessed September 14, 2020. 

https://www.cdc.gov/flu/symptoms/flu-vs-covid19.htm

Help patients with upper respiratory infections choose an OTC product that’s right for them.

Combatting the Common Cold

Over 80 autoimmune diseases affect an estimated 14.7 million to 23.5 million people in the United States.

The mainstays of therapy consist of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, disease-modifying antirheumatic drugs (DMARDs), and anti–tumor necrosis factor (TNF)–Î± biologics, but various products over the counter also help relieve symptoms. Pharmacists can help patients select the appropriate OTC medications in light of special considerations related to their conditions.

For rheumatoid arthritis (RA) and other autoimmune diseases, NSAIDs can be a good starting point for relieving pain and inflammation, said Wendy Ramey, BSPharm,RPh,CSP,clinicalpharmacist with a specialty in inflammatory conditions at University of Kentucky’s specialty pharmacy and infusion services in Lexington. For some conditions, such as ankylosing spondylitis, most insurance companies require that patients try OTC or prescription NSAIDs before being approved to move on to biologics, she said.

Ramey recommends that patients limit OTC NSAID use to short periods. “If they need to go beyond 2 or 3 weeks of everyday use, then they’re going to need to talk to us about some other kind of treatment to take care of their pain,” she said.

Community pharmacists who notice patients with autoimmune diseases consistently buying these OTC products should initiate a discussion regarding use, said Jessica Farrell, PharmD, clinical pharmacist at the Center for Rheumatology at the Albany College of Pharmacy and Health Sciences in New York. “If [patients are] using lots of NSAIDs consistently with a DMARD-methotrexate, hydroxychloroquine, sulfasalazine-or a TNF inhibitor...then maybe that DMARD or biologic is not adequate,” Farrell said. Patients should be advised to speak with their provider about trying a different therapy. Patients also should take a histamine-2 receptor blocker or proton pump inhibitor (PPI) because of gastrointestinal toxicities related to NSAIDs, she advised.

Pharmacists can recommend other OTC products to manage symptoms. For patients with inflammatory arthritis, Farrell encourages use of OTC topical pain-relief prod- ucts such as lidocaine patches and diclofenac gel. “These are great options for patients who have more mild disease or in smaller joints or for small flares that don’t require systemic therapy,” she said.

Pharmacists also can guide patients toward OTC products to treat the dry mouth and eyes associated with SjÃ¶gren syndrome. “Many of our patients [with] other au- toimmune diseases have overlap SjÃ¶gren syndrome,” Farrell reported. Various products treat dry mouth, including mouthwashes, gums, and toothpastes, and it often takes trial and error to find what works best for each patient, she said. Patients with SjÃ¶gren may need help finding the right eye drops, whether they need a preservative-free product or one for sensitive eyes. Gel-like drops can be particularly helpful for patients with severe nighttime dryness that interferes with sleep, Farrell said.

Mild injection site reactions in patients on injectable therapies can be treated with OTC topical steroids or antihistamines, according to Farrell.

For patients who complain of insomnia, which can be caused by an autoimmune disease or its treatment, Ramey recommends melatonin products rather than antihistamines, which can have other unwanted effects.

Various nutritional supplements also play a role in managing autoimmune diseases. Folic acid supplementation is crucial to reduce the gastrointestinal and liver toxicities of methotrexate therapy in patients with RA. Although most patients take prescription folic acid, Farrell said, some use the OTC version. Recommendations on amounts vary, but common regimens consist of 1 mg daily or 5 mg once weekly.

Some data suggest that cherries and cherry extract products have antioxidant properties and reduce inflammation in patients with gout. Farrell commonly adds those products as an adjunct for patients taking uric acid–lowering therapies, such as allopurinol and febuxostat, who need additional urate-lowering therapy but for whom adverse effects preclude increased doses.

Patients taking NSAIDs should be taught to carefully check labels of OTC combination products to prevent overdosing on NSAIDs, Farrell said. “That’s one of the things that I teach my patients a lot about: reading labels and how to recognize if they’re taking products that have multiple drugs in them, so they’re not double dosing on ibuprofen or taking ibuprofen and naproxen at the same time,” she said.

Patients with SjÃ¶gren should be ad- vised to avoid OTC products containing decongestants and first-generation antihistamines, which can exacerbate dryness, Farrell said: “Sometimes patients take Tylenol PM; they don’t realize that it has diphenhydramine, so it’s drying them out even more.” For relief from seasonal allergy symptoms, second-generation antihistamines are preferable, she said.

Patients with RA who are looking for immune-boosting supplements also need to scrutinize labels. Ingredients such as zinc and vitamin C are fine to take, Farrell said, but pharmacists should warn patients to steer clear of products that contain astragalus, an herb that increases TNF-É.

An important drug interaction in this population occurs between immuno-suppressant mycophenolate mofetil and PPIs, Farrell noted. PPIs can reduce absorption of mycophenolate mofetil, which requires an acidic environment for optimal absorption, so patients should take mycophenolate mofetil at least 90 minutes before the PPI. Pharmacists are in an ideal position to alert patients about this interaction, she said, because physicians might not be aware that their patients are taking OTC PPIs.

To avoid toxicity, acetaminophen use should be limited to 2 g per day in patients taking drugs that are metabolized by the liver, Ramey said. Farrell noted that in patients taking hydroxy- chloroquine, any OTC product potentially associated with increased risk of QTc prolongation, such as pseudo-ephedrine, could be problematic.

“For the most part, we [in the field of rheumatology] are very lucky to have drugs that don’t cause us very many [drug interaction] problems,” Ramey said.

Pharmacy software might flag an interaction between methotrexate and NSAIDs, but that is not clinically relevant in this patient population, Farrell said. NSAIDS can prevent excretion of methotrexate, which is used in high doses in oncology, and result in toxicity, but that is not an issue at the doses used in autoimmune diseases, she said.

Because so many patients with autoimmune disease take immunosuppressants, pharmacists counseling them should be on the lookout for infections.

“If a patient with an autoimmune disease is coming in looking for something to treat a possible infection, like [OTC] bactericidal ointments or creams, that would be the first clue that something needs to be addressed with their doctor,” Ramey said. “Because most of our medications increase the risk of infection, we always want to know if a patient has a cut or a bug bite that is starting to look infected; that is our biggest concern.”

Patients on immunosuppressants who want to buy OTC cough or cold products should be reminded that their current treatments prevent them from fighting infections. “If they’re on methotrexate, sometimes, if it’s a very mild infection, we might not have to hold it, but if they’re on biologics, they definitely should hold during an infection.”

The right products can help manage symptoms of autoimmune diseases.

Offer Patients OTC Pointers

In the ever-changing world of diabetes devices, pharmacists need to stay on top of developments so that they can answer patients’ questions about what is available.

Continuous glucose monitors (CGMs) are used increasingly to help patients with diabetes monitor and treat blood sugar levels, said Panteha Kelly, RPh, BCACP, APh, CDE, a clinical pharmacist specialist and clinic coordinator at the University of California, San Diego, Health Diabetes Self-Management Clinic in La Jolla, California.

Continuous scanning, or real-time, CGMs provide a constant reading of interstitial glucose to a receiver or smart device, and alarms alert the wearer when glucose is approaching patient thresholds for hyper- or hypoglycemia. In contrast, intermittently scanning, or flash, CGMs require the user to swipe the transmitter over the sensor to display data from the previous 15 minutes, including trend arrows showing whether blood sugar is rising or dropping and how quickly; they do not have alarms or alerts.

The most popular CGM on the market is the Dexcom G6 system. Unlike earlier Dexcom models and the other real-time CGMs, Guardian Connect and Eversense, Dexcom G6 does not require finger sticks for calibration. Eversense requires implant and removal every 3 months in office by a provider.

Jennifer Trujillo, PharmD, FCCP, BCPS, CDE, BCADM, believes that once it has been on the market for a while longer and gets approval for longer wear (6 or 12 months), it will likely be used more. Trujillo is an ambulatory care pharmacist and certified diabetes care and education specialist at the University of Colorado Anschutz Medical Campus Center for Adult Diabetes Care and Research in Aurora.

Freestyle Libre is the only flash CGM; it costs less than the Dexcom G6 and is easier to use, Trujillo said. Kelly cautioned that it must be scanned at least once every 8 hours to save the data for review later.

Real-time CGMs are usually preferred for patients with type 1 diabetes, who need close monitoring of their blood glucose and alerts, whereas flash CGMs are appropriate for patients with type 2 diabetes. The alarms on a real-time CGM can be lifesaving by, for example, alerting patients with hypoglycemic unawareness when their blood sugar is dropping, so they know not to drive, Kelly said.

“Real-time CGMs also allow data sharing, so it’s a great option for kids so that their parents can have the CGM data on their phones, as well,” Trujillo said.

About half of Trujillo’s patients with type 1 diabetes use insulin pumps. “The evidence at this point indicates that patients can achieve good glucose control in a variety of different ways, either through injection therapy or through insulin pump therapy, so I think it requires a thoughtful conversation between the patient and the provider,” she said.

Hybrid closed-loop systems combine the functionality of a CGM with a pump to automate insulin delivery based on real time glucose values. The first hybrid closed-loop system, Medtronic’s MiniMed 670G, was approved in 2016. This CGM communicates with an insulin pump designed to decrease or stop insulin when glucose is low and increase insulin delivery when glucose is high, without input from the user.

Tandem’s t:slim X2 Insulin Pump with Basal-IQ technology was approved in 2018 as an insulin pump and CGM: The pump suspends insulin delivery if the CGM detects glucose falling below a predefined threshold.

Tandem’s next advance, approved in December 2019, is Control-IQ technology, which automatically increases, decreases, or suspends delivery of basal insulin based on insulin delivery history, CGM data, and predicted glucose values. Control-IQ uses the Dexcom G6 CGM with the t:slim pump.

For patients who have traditional insulin pumps, Trujillo said, providers track glucose trends over 3 or 6 months and work with the patients to adjust basal insulin rates for different times of day. “[This is as] opposed to the hybrid closed-loop insulin pumps, where the basal rates are constantly changing based on the glucose readings from the CGM,” she explained. “There is encouraging evidence that the hybrid closed-loop systems can improve glucose variability, particularly overnight.”

Patients are slowly transitioning to newer models but still represent a small percentage of patients with type 1 diabetes, Trujillo said.

Patients should be carefully selected, according to Kelly. “I can’t give a closed-loop system to just anybody at this time, because if it malfunctions [or] if someone has a low health literacy, it can be dangerous.”

Medicare typically covers CGMs for patients with diabetes who test their blood sugar at least 4 times a day and take multiple daily doses of insulin, Trujillo said. She believes that almost all patients with type 2 diabetes can benefit from a flash CGM. “Knowledge is very powerful,” she said, “and when you’re able to see your glucose values all day long without sticking your finger, that information can create important behavioral changes and can create more understanding of how medications are working and how different behaviors are influencing glucose.”

Patients can observe how stress, lack of sleep, and lack of exercise negatively affect their blood glucose control, whereas exercise and healthy eating improve glucose control, she said: “Seeing that over time can certainly improve glucose management overall.”

The 2 most popular CGMs can be dispensed in pharmacies, which places pharmacists in an ideal position to counsel patients about these devices, especially because most patients with type 2 diabetes are managed by primary care providers who may be less familiar with diabetes technology advances, Trujillo said.

Kelly emphasized that patients need to understand that when starting to use a CGM, they cannot draw conclusions regarding diabetes management until they have collected 10 to 14 days of data. To capture nighttime data, she noted that patients starting to use the Freestyle Libre should scan their device both right before going to bed at night and upon waking up in the morning.

Trujillo encourages pharmacists to learn more about CGMs by taking continuing education courses and watching tutorials on the manufacturers’ websites. “It’s challenging to keep up on the latest and greatest but certainly important for a frontline health care provider like a pharmacist to do so,” she said.

Pharmacists must be tuned in to the latest technology for patients who monitor blood glucose.