One major HIV drug combo fails in trial, others succeed

Daridorexant is approved to treat insomnia in adults who have difficulty with sleep onset or maintenance.

Clinicians are seeking ways to reduce opioid exposure in a variety of settings. Could the use of acetaminophen before opioid use reduce opioid treatment duration in the inpatient setting?

The FDA approved efgartigimod, which is being sold under the brand name Vyvgart and could foment price competition with Soliris (eculizumab) and other treatments usually reserved for severe or refractory cases.

A combination of two targeted cancer drugs showed unprecedented, “clinically meaningful” activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.

The pill, Paxlovid, showed an 88% decrease in hospitalization and death for those taking it 5 days after experiencing COVID-19 symptoms.

The benefits of probiotics do not necessarily transfer to the clinical setting for vulvovaginal candidiasis, according to a recent review.