The total number of illicit fentanyl seizures by law enforcement in the United States surged by more than 1700% between 2017 and 2023, according to new data published in the International Journal of Drug Policy.1
In 2023, a staggering 115.6 million fentanyl pills were seized, representing nearly half (49%) of all seizures in the nation. This marks a dramatic 4-fold increase in pill seizures compared to just 7 years prior—a change that underscores an alarming trend in the opioid epidemic.
Key Takeaways
- There was a massive surge in fentanyl seizures by law enforcement between 2017 and 2023, with the total number of seizures increasing by over 1700%.
- In 2023, nearly half (49%) of all fentanyl seizures were pills. Fentanyl pills are especially dangerous because they can be easily mistaken for legitimate prescription drugs, creating a significant risk of accidental overdose.
- The West currently has the highest fentanyl seizure rates compared to other regions in the US, but others are catching up. This suggests a nationwide spread of illicit fentanyl, with pills becoming more dominant.
“About half of seized fentanyl is now in pill form, suggesting that the illicit drug landscape has rapidly changed,” said Joseph J. Palamar, PhD, MPH, lead study author, associate professor in the Department of Population Health at NYU Langone Health, and deputy director of the National Drug Early Warning System.2 “Fentanyl in pill form not only makes it easier for people to initiate use, but also increases the chances that people who buy illicit pills could be unintentionally exposed to fentanyl since it is commonly present in counterfeit pills pressed to resemble oxycodone, Xanax, or even Adderall.”
Although rates of synthetic opioid-related deaths over time and across regions have been widely evaluated, investigators hypothesized that other indicator data could lend important insights into guiding prevention and harm reduction efforts in the illicit fentanyl landscape, as well as understanding overdose mortality trends. To gather this data, investigators compared how fentanyl seizures differed across regions in the US.
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Annual trends in fentanyl seizures, both nationwide and stratified across the West, East, South, and Midwest, were gleaned from the High Intensity Drug Trafficking Areas program from 2017 to 2023. Investigators measured seizures across 8 indicators, which included the number of powder seizures; the number of pill seizures; the total weight of seizures; the number of pills seized; and the percentage of the number of pill seizures relative to the number of total seizures.
Overall, the number of fentanyl seizures increased from 1305 in 2017 to 23,529 in 2023, representing a staggering 1703.0% increase (adjusted annual percentage change [AAPC], 60.7; 95% CI, 47.6-74.9). This translated to a total weight of 42,927.3 kg of fentanyl and 177,535,917 fentanyl pills seized in the 7-year time frame.