New drug for COPD lets patients breathe more easily
February 23rd 2004The FDA recently approved tiotropium (Spiriva HandiHaler, Pfizer/Boehringer-Ingelheim) inhalation powder for the long-term, once-daily, maintenance treatment of bronchospasm associated with COPD, including bronchitis and emphysema. In the airways, tiotropium inhibits muscarinic (M3) receptors at the smooth muscle, leading to bronchodilation. The manufacturer anticipates that tiotropium will be available in pharmacies by mid-year.
New drug is first to be OK'd for bipolar depression
January 26th 2004Clinicians can now treat patients with bipolar depression using the first drug approved in the U.S. for this indication. The FDA recently approved olanzapine/fluoxetine (Symbyax, Eli Lilly) for the treatment of depressive episodes associated with bipolar disorder. Symbyax is currently available in pharmacies.