AUSTEDO (deutetrabenazine), Teva
Indications: A vesicular monoamine transporter 2 (VMAT2) inhibitor indicated for the treatment of chorea associated with Huntington’s disease.
Dosage: Starting dose is 6 mg once daily. Titrate up at weekly intervals by 6 mg per day to a tolerated dose that reduces chorea, up to a maximum recommended daily dosage of 48 mg (24 mg twice daily). Administer total daily dosages of 12 mg or above in two divided doses. Take with food.
Contraindications: Suicidal, or untreated/inadequately treated depression; hepatic impairment; or concurrent MAOIs, reserpine, or tetrabenazine.